The aim of this quantitative research was to examine the relationship between job satisfaction, job burnout and the experience of participating in the supervision of professionals in a social welfare center. A total of 71 experts between the ages of 25 and 65, who are currently employed at the Social Welfare Center in Zagreb, participated in the research. The results showed a negative relationship between job satisfaction and job burnout among professionals. Furthermore, the results didn't show the difference in the degree of job satisfaction and the degree of a job-related burnout, considering the experience of participation in supervision. Nevertheless, the results established the existence of a difference in the degree of job satisfaction and the degree of job-related burnout considering the fact of being currently involved in supervision. Thus, it can be concluded that those professionals who are currently involved in supervision are more satisfied with their work and are at a lower risk of job burnout. The obtained results emphasize the need to maintain regular and effective supervision, considering that it was shown that it is not enough to have the experience of participating in supervision, but it is necessary to provide supervision and participate in it as often as possible. In this way, professionals are provided with the necessary support in protecting and preserving their mental health, especially in the form of preventing job burnout and increasing their job satisfaction. Also, the obtained results can serve as an incentive for further research and spreading awareness about the importance of ensuring supervision in social welfare institutions.