Depression is a very common disorder that is increasingly appearing in children and adolescents. It is estimated that, together with anxiety, 54.8% of young people in the Republic of Croatia have symptoms of depression. The Diagnostic and Statistical Manual of Mental Disorders distinguishes several types of depressive disorders with different emotional, physical, cognitive, and behavioral symptoms. The most common symptoms of depression in children and adolescents are sadness, low mood, sorrow and irritability. Depression often occurs in combination with other disorders; eating disorders, anxiety disorders, behavioral disorders. The onset of depression can be attributed to various biological, psychological, cognitive, behavioral, family or social elements. In addition to the child himself, the parents or people close to the child also play an important role in the diagnosis of depression, whose information also plays a major role in the clinical assessment. Different approaches are used in treatment; pharmacotherapy and psychotherapy and the combinations. It is important to build resilience through strengthening different skills in young people, in order to soothe the consequences of depression. Social worker has a very important role in the prevention and treatment of depressive disorders in children and adolescents, by carrying out numerous institutional and extra-institutional procedures within their jurisdiction.