Abstract | Alzheimerova bolest (AB) je progresivna i neizlječiva neurodegenerativna bolest koja zahvaća sve veći broj ljudi u svijetu, posebno populaciju iznad 65 godina starosti. Glavni simptomi AB su gubitak pamćenja, pad kognitivnih sposobnosti i promjene u osobnosti koji vode do nemogućnosti samostalnog funkcioniranja. Cilj rada bio je procijeniti prehrambene navike oboljelih od Alzheimerove bolesti i usporediti ih sa zdravim osobama. U istraživanju je sudjelovalo 10 osoba oboljelih od AB prosječne starosti 75,9 ± 11,6 godina (40 % muškaraca i 60 % žena ) i 35 zdravih osoba, prosječne starosti 61,0 ± 9,6 godina (37,1 % muškaraca i 62,9 % žena). Oboljeli od AB su značajno stariji (p<0,001), imaju značajno niži indeks tjelesne mase (23,4 ± 3,2 kg/m2, p=0,002), imaju izraženiji gubitak na masi (30,0 % vs 17,0 %), imaju više problema sa žvakanjem (p=0,012) i veći broj simptoma povezanih s demencijom (4,5 ± 3,3 vs 2,5 ± 2,2, p=0,029) od zdravih osoba. Također, nikada ne preskaču obroke (100 % vs 42,9 %, p=0,002) i imaju više obroka u danu (3,4 ± 0,7 vs 2,5 ± 0,5, p=0,003). Karakteristike prehrane oboljelih od AB su bolje od zdravih osoba: DASH dijeta (5,2 ± 0,9 vs 4,2 ± 1,3 bodova, p=0,042), MeDi dijeta (AB i ostale demencije 13,5 ± 3,1 vs 10,5 ± 4,2 bodova, p=0,031) i MIND dijeta (6,2 ± 1,0 vs 5,5 ± 1,5 bodova). |
Abstract (english) | Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, mostly affecting population older than 65 years. Symptoms like loss of memory, cognitive decline and personality change are the most common, all leading towards hindering person's ability to function independently. The aim was the assessment of dietary habits of AD patients in comparison to healthy elderly people. 10 AD patients aged 75.9 ± 11.6 years (40 % men and 60 % women), and 35 healthy elderly people aged 61.0 ± 9.6 years (37.1 % men and 62.9 % women) participated in the study. AD patients are significantly older (p<0.001), have lower Body Mass Index (23.4 ± 3.2 kg/m2, p=0.002), with more emphasized weight loss (30.0 % vs 17.0 %), more dental problems (p=0.012) and more symptoms related to dementia (4.5 ± 3.3 vs 2.5 ± 2.2, p=0.029) from healthy elderly. Also, they never skip meals (100 % vs 42.9 %, p=0.002 %) and have more meals per day (3.4 ± 0.7 vs 2.5 ± 0.5, p=0.003). Dietary characteristics of AD patients are better from healthy elderly: DASH diet (5.2 ± 0.9 vs 4.2 ± 1.3 points, p=0.042), MeDi diet (AD and other dementias 13.5 ± 3.1 vs 10.5 ± 4.2 points, p=0.031) and MIND diet (6.2 ± 1.0 vs 5.5 ± 1.5 points). |