Abstract: Structural interpretation of the 2D seismic reflection sections and exploration well data enabled determination of the geometry, kinematics and spatial distribution of faults and associated structures in the eastern part of Slavonija-Srijem Depression. The constructed 3D structural model consists of the structure contour maps - Base Neogene, Base Pannonian and Base Plio-Quaternary, three regional stratigraphic horizons that corelate with important changes in tectonic evolution in the Croatian part of Pannonian basin system. In this work main deformation structures were also reconstructed. Results indicate that structures in the study area were firstly created during the phase of opening of the Slavonija-srijem depression during the Lower and Middle Miocene, as a result of regional extension and then changed during tectonic inversion that occurred in Pliocene and Quaternary. Eleven structural units were defined on the structural conture maps. Structural units Vinkovci, Berak and Bapska are defined as grabens that were formed during the extensional phase in Lower and Middle Miocene. In this phase syncline Nijemci and horst Đeletovci were also formed. During the compressional phase during the Pliocene and Quaternary in the east of the research area Bokšić anticline was formed. Based on interpreted data the structural evolution of the eastern part of Slavonija-Srijem Depression is reconstructed. The depression was formed by normal faulting in phase of intensive extension during Lower and Middle Miocene, was followed by sinsedimentary normal extension in upper Miocene. In the phase of structural reactivation and tectonic inversion that commenced during Pliocene and Quaternary mild inversion occurred with reverse faulting only sporadically occurred in the east of study area as part of Bokšić anticline.