Dental implantology, along with dental medicine in general, is progressing every day, which automatically changes its standards and principles. Continuous material improvement, indication widening, therapist education and rising of patients’ interest in this kind of edentulousness treatment (both partial and total) have resulted in very high number of possibilities offered by implantological principles, so it is not surprising to see the tendency of further profession development. Success of this kind of rehabilitation can be followed decades into the past, but it is also logical that, together with the progress of all the elements brought up earlier, the definition of therapy success itself needs to be revised. One of the key indicators of an implant supported prosthetic device’s stability and adequate maintenance is the peri-implant tissue integrity. Since the beginnings of dental implantology until now, a continuously increasing number of factors is present, the factors which are, according to current evidence, considered to have a strong impact on the peri-implant tissue integrity. There is no universal principle that would eliminate all the risk factors and complications, hence, it is preferable to simplify and subdue every potential clinical scenario during systematization, so the surgical (as well as prosthetic) part of the protocol would be feasible. Exactly that is the purpose of the zerobone loss concept, which tends to take all the available facts into consideration, so that all the known risks would be eliminated and the patient could be rehabilitated appropriately.