AIM: The purpose of the study was to examine the prevalence of some clinical features in subjects with Class I and orthodontic malocclusion Class II/1 and Class II/2 and to determine the differences between them (if any). The purpose of the study was to describe some of the characteristics of the occlusion and dental arches of the subjects on the plaster models mounted in the articulator, to make an Cephalometric analysis and to carry out instrumental analysis using the method of ultrasonic pantography. Also, the purpose of the study was to obtain information about the self-assessed intensity of the characteristics of the stomathognatic system by completing the Craniomandibular disorderds (CMD) questionnaire. PARTICIPANTS AND METHODS: The study included a target group of 90 adolescent patients aged 15-20 divided into three groups: a group with malocclusion Class II/1 (30 patients), a group with malocclusion Class II/2 (30 patients) and a control group of healthy individuals with normoclussion (30 respondents). Diagnostic protocol included: CMD questionnaire, cephalometric analysis, evaluations of plaster models, clinical examination and manual analysis by Bumman, as well as instrumental analysis using Arcus Digma system (KaVo EWL GmbH, Leutkirch Germany). In statistical data processing, the p-value less than 0.05 was considered statistically significant. The data processing itself was performed using the STATISTICA 64 statistical analysis software package, version 10 for Windows. RESULTS: The average age of class II/1 subjects is 17.1 years, class II/2 is 17.3 years, and control group subjects are 18 years. Minimal dysfunction according to the so-called Helkimo index was recorded in 83.3% of class II/1 respondents, 76.7% of class II/2 respondents, and 43.3% subjects in class I. None of the subjects had moderate or severe dysfunction according to Helkimo index. The prevalence of painful muscles at palpation occurs in 63.3% of malocclusion Class II/2 subjects, 13.3% of malocclusion Class II/1 subjects, and in 10% of subjects in control group. The prevalence of deviation is more common in subjects with Class II/2 malocclusion than in other groups. Namely, 64.7% of all subjects with this malocclusion belong to this group. Deflection occurs most often in class II/1 (51.3% of all subjects with deflection). Reduced mouth opening is also associated with a group with Class II/1 malocclusion. Namely, 72.2% of subjects with this problem belong to this group. TMJ clicking is present in 73.3% of subjects with malocclusion Class II/1, in 80% of subjects with malocclusion Class II/2, and in 16.7% subjects in the control group. Enamel abrasion is prevalent in the malocclusion Class II/2, while enamel and dentin abrasion is present in the malocclusion Class II/1. Overjet is, on average, the largest in malocclusion Class II/1 (9 mm), in the control group is more than twice smaller (4.1 mm), and in malocclusion Class II/2 is 2.1 mm. Overbite is on average the largest in the malocclusion Class II/2 group (7.3 mm), in malocclusion Class II/1 it is slightly smaller (5.9 mm), and in the control group is 2.3 mm. The average depths of the Spee curve in malocclusion Class II/1 were 3.6 mm (for left and right side), in malocclusion Class II/2, the average on the right is 4.4 mm and on the left 4.5 mm, while in the control group, the average on the right is equal to the average on the left (2.4 mm). The average incisor inclination measured on Cephalometric analysis is lowest in the malocclusion Class II/2 (100.3°), higher in the control group (111.5°), while the largest in the malocclusion Class II/1 (114.4°). The horizontal growth pattern characterizes primarily male respondents, namely 86.8% of them belong to this growth pattern, and to the vertical pattern only 13.2%. In female subjects, the horizontal pattern occurs in 57.7%, and vertical in 42.3%. Differences of CR-MI movements by group are statistically significant in verticals and transversals of the right and left condyle. The largest inclinations of the condyle path were measured in the control group (39.6°on the right and 39.9° on the left), followed by the malocclusion Class II/2 (27.3° on the right and 25.2° on the left), and at least in the malocclusion Class II/1 (20.1° on the right and 23.9° on the left). The highest values of Benett's angle are in the malocclusion Class II/1 (11.9° on the right, and 10.5° on the left). The highest values of Benett's angle were measured in a group with Class II/I malocclusion (11,9° on the right and 10,5° on the left). The angle of incisal guidance, also differs statistically significantly by groups, but only on the left. The highest average value of the incisal guidance angle is in the Class II/1 malocclusion group on the left (62.7°). The mouth opening is on average 38.2 mm in the Class II/1 malocclusion group, and in the other two groups it is almost equal (42.6 mm in the group with malocclusion Class II/2 and 42.8 mm in the control group). Statistically significant correlations between the parameters studied in this study were also found. CONCLUSION: Based on the results of this study, it can be concluded that there are some differences in clinical signs and characteristics between subjects with malocclusions Class II/1, Class II/2 and Class I. The incidence of parameters analyzed by clinical examination (pain on palpation of muscles, deviation/deflection, TMJ clicking, teeth abrasion) was higher in class II subjects than in the control group. Also, higher values of overjet, overbite and Spee curve depth in class II subjects were found. The results related to the self-assessed intensity of the characteristics of the stomatognathic system assessed by CMD questionnaire completed by the participants and the results obtained by other methods used in the study can not be excluded as a random finding since questionnaries and protocols used were not standardized.