By prolonging life expectancy, we are facing new challenges that age and aging population bring. The increase in the share of the elderly population has spurred accelerated professional and scientific interest in the field of gerontology. The impact of genetics and the environment on accelerated aging is becoming the interest of numerous new studies. The concept of inflammaging or chronic inflammation of lower intensity and immunosenscence or progressive weakening of the immune system is now set in the center of studies of chronic age – related diseases. One of the most common chronic inflammatory conditions in the body is periodontal disease or periodontitis. Periodontitis is an inflammation of the supporting tissue of the tooth that affects the soft tissue, periodontal ligament and alveolar bone, and is caused by the present bacterial pathogenic biofilm that triggers a chronic inflammatory response that leads to destruction of these tissues. The presence of chronic inflammation in the body can affect the modification of the immune response and cause its accelerated aging, which leads to various other inflammatory and chronic conditions that lead to weakening and aging of the body, the so-called frailty. By promoting healthy living habits and also promotion of oral health it is possible to slow down aging and influence the quality of life that is becoming an increasing priority of an aging society.