Periodontal diseases are diseases of the attachment apparatus of the teeth most often caused by infection with bacteria of the oral cavity, but they can have other causes too. Today, about 50% of the population suffers from periodontitis, and its severe form is the sixth most common disease in the world. It is known that they can affect the occurrence of other conditions in the body, and it seems that this also applies to inflammatory skin diseases. These are diseases with inflammation as their pathogenesis and their etiology can be different - infectious, autoimmune, neoplastic, traumatic, allergic. Systemic lupus erythematosus, psoriasis, rheumatoid arthritis, pemphigus vulgaris, pemphigoid, systemic sclerosis, bullous epidermolysis and atopic diseases were included in this analysis. Periodontal disease appears to affect the onset and progression of inflammatory skin diseases. On the other hand, according to some research, inflammatory skin diseases can worsen the condition of periodontitis, which is a chronic disease, and reduce the success of oral hygiene and periodontal therapy in its control. Different mechanisms have been proposed by which these two groups of diseases can interact with each other, either in condition or progression. Good and consistent oral hygiene leads to better general health of the organism. If the association between periodontitis and certain inflammatory skin diseases is established, additional oral health care and appropriate periodontal therapy could be beneficial to these patients whom the condition they are suffering from can cause great difficulties. Although there are studies on this topic, there are still few ones, and the results obtained differ from each other. Further research on the association of these diseases is needed to draw valid conclusions.