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Scientific paper - Review paper
Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports
International Journal of Molecular Sciences, 24 (2023), 4; 4039. https://doi.org/10.3390/ijms24044039
Bešlić, Iva; Lugović-Mihić, Liborija; Vrtarić, Alen; Bešlić, Ante; Škrinjar, Ivana; Hanžek, Milena; Crnković, Danijel; Artuković, Marinko

Institutional repository: University of Zagreb School of Dental Medicine Repository

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Bešlić, I., Lugović Mihić, L., Vrtarić, A., Bešlić, A., Škrinjar, I., Hanžek, M. ... Artuković, M. (2023). Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports. International Journal of Molecular Sciences, 24. (4). doi: 10.3390/ijms24044039

Bešlić, Iva, et al. "Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports." International Journal of Molecular Sciences, vol. 24, no. 4, 2023. https://doi.org/10.3390/ijms24044039

Bešlić, Iva, Liborija Lugović Mihić, Alen Vrtarić, Ante Bešlić, Ivana Škrinjar, Milena Hanžek, Danijel Crnković and Marinko Artuković. "Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports." International Journal of Molecular Sciences 24, no. 4 (2023). https://doi.org/10.3390/ijms24044039

Bešlić, I., et al. (2023) 'Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports', International Journal of Molecular Sciences, 24(4). doi: 10.3390/ijms24044039

Bešlić I, Lugović Mihić L, Vrtarić A, Bešlić A, Škrinjar I, Hanžek M, and sur.. Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports. International Journal of Molecular Sciences [Internet]. 2023 February 17 [cited 2024 November 28];24(4). doi: 10.3390/ijms24044039

I. Bešlić, et al., "Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports", International Journal of Molecular Sciences, vol. 24, no. 4, February 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:068587. [Accessed: 28 November 2024]

Metadata
Title (english)Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports
AuthorIva Bešlić
AuthorLiborija Lugović-Mihić
MBZ: 215056
AuthorAlen Vrtarić
AuthorAnte Bešlić
AuthorIvana Škrinjar
AuthorMilena Hanžek
AuthorDanijel Crnković
AuthorMarinko Artuković
Author's institutionUniversity North
Author's institution(Sestre milosrdnice University Hospital Center)
Author's institution(Zagreb University Hispital Center)
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Melatonin is the main hormone that regulates the sleep cycle, and it is mostly produced by the pineal gland from the amino acid tryptophan. It has cytoprotective, immunomodulatory, and anti-apoptotic effects. Melatonin is also one of the most powerful natural antioxidants, directly acting on free radicals and the intracellular antioxidant enzyme system. Furthermore, it participates in antitumor activity, hypopigmentation processes in hyperpigmentary disorders, anti-inflammatory, and immunomodulating activity in inflammatory dermatoses, maintaining the integrity of the epidermal barrier and thermoregulation of the body. Due predominantly to its positive influence on sleep, melatonin can be used in the treatment of sleep disturbances for those with chronic allergic diseases accompanied by intensive itching (such as atopic dermatitis and chronic spontaneous urticaria). According to the literature data, there are also many proven uses for melatonin in photoprotection and skin aging (due to melatonin’s antioxidant effects and role in preventing damage due to DNA repair mechanisms), hyperpigmentary disorders (e.g., melasma) and scalp diseases (such as androgenic alopecia and telogen effluvium).
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 4, 4039
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24044039
URN:NBNurn:nbn:hr:127:068587
Publication2023-02-17
Document URLhttps://www.mdpi.com/1422-0067/24/4/4039
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-05-11 09:36:57