Dental age estimation is a big part of forensic odontology. Prenatal, newborn, children and adolescent dental age assesment is based on phases of development of the teeth, while in the adult dentition degenerative changes due to aging are observed. There are several dental age assesment methods: morphological, radiological and biochemical. The most significant change that occurs with aging is the reduction of pulp cavity due to physiological secondary dentin deposition. Additionally, as a response to pathological stimuli, tertiary dentin is formed. Increased incidence of denticles within the endodontic space has also been observed. Dental age estimation based on pulp cavity changes can be carried out through the pulp-tooth ratio, as well as by measuring the coronal pulp cavity index. Kvaal et al. measured the lenght of tooth, pulp and root, as well as width of root and pulp on three different levels in periapical images of six teeth. Based on this, they generated formula for dental age estimation: age=129.8 – 316.4M – 66.8(W – L). Cameriere et al. used pulp-tooth area ratio, and with the development of CBCT technology, volumetric measurements were introduced. Drusini et al. used a different approach using Ikedas formula for dental age estimation by measuring the height of coronal pulp cavity (CPCH) and the height of the tooth crown (CH). Tooth coronal index was calculated using the formula: TCI = CPCH x 100/CH. Dental age estimation methods based on changes of the endodontic space are considered non-invasive and straightforward, although further research is needed to enhance result accuracy.