prikaz prve stranice dokumenta Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report
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Scientific paper - Original scientific paper
Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report
Frontiers in Oncology, 13 (2023); 1260989. https://doi.org/10.3389/fonc.2023.1260989
Adžić, Gordan; Prejac, Juraj; Pleština, Stjepko

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Adžić, G., Prejac, J. & Pleština, S. (2023). Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report. Frontiers in Oncology, 13.. doi: 10.3389/fonc.2023.1260989

Adžić, Gordan, et al. "Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report." Frontiers in Oncology, vol. 13, 2023. https://doi.org/10.3389/fonc.2023.1260989

Adžić, Gordan, Juraj Prejac and Stjepko Pleština. "Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report." Frontiers in Oncology 13 (2023). https://doi.org/10.3389/fonc.2023.1260989

Adžić, G., Prejac, J. and Pleština, S. (2023) 'Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report', Frontiers in Oncology, 13. doi: 10.3389/fonc.2023.1260989

Adžić G, Prejac J, Pleština S. Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report. Frontiers in Oncology [Internet]. 2023 October 10 [cited 2024 July 09];13. doi: 10.3389/fonc.2023.1260989

G. Adžić, J. Prejac and S. Pleština, "Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report", Frontiers in Oncology, vol. 13, October 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:515500. [Accessed: 09 July 2024]

Metadata
Title (english)Long-term follow-up of complete remission in a patient with advanced hepatocellular carcinoma treated with sorafenib: a case report
AuthorGordan Adžić
AuthorJuraj Prejac
AuthorStjepko Pleština
Author's institution(Zagreb University Hispital Center)
Author's institutionUniversity of Zagreb
School of Medicine
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Introduction: Hepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver cancer and can be caused by well-known risk factors, including infection with hepatitis B and C viruses, alcohol intake, and metabolic syndrome. The overall prognosis remains poor with a median survival of 1 year for symptomatic advanced-stage cases treated with systemic therapies. Case description In July 2020, a 73-year-old male patient presented at our institution with mild abdominal pain and an attack of intense cold. After a radiological workup, the diagnosis of HCC located in the caudate lobe was established. The patient underwent atypical caudate lobe resection, and pathology confirmed the diagnosis of grade 3 HCC. Postoperative MRI showed a new metastasis in the 6th liver segment 1.3 cm in diameter, and a PVT progression which now affected the whole right lobe. The patient was started on sorafenib and demonstrated a complete response which still lasts for more than two years. Conclusion: We present a rare case of a patient who demonstrated a complete response to sorafenib treatment in advanced HCC with unfavorable prognostic factors.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFrontiers in Oncology
Numberingvol. 13, 1260989
e-ISSN2234-943X
DOIhttps://doi.org/10.3389/fonc.2023.1260989
URN:NBNurn:nbn:hr:127:515500
Publication2023-10-10
Document URLhttps://www.frontiersin.org/articles/10.3389/fonc.2023.1260989/full
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-07-02 11:20:01