prikaz prve stranice dokumenta Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration
  Download
PDF 500.79 KB
Scientific paper - Original scientific paper
Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration
Journal of Clinical Periodontology, 46 (2019), S21; 82-91. https://doi.org/10.1111/jcpe.13123
Sanz, Mariano; Dahlin, Christer; Apatzidou, Danae; Artzi, Zvi; Božić, Darko; Calciolari, Elena; De Bruyn, Hugo; Dommisch, Henrik; Donos, Nikos; Eickholz, Peter; Ellingsen, Jan E.; Haugen, Håvard J.; Herrera, David; Lambert, France; Layrolle, Pierre; Montero, Eduardo; Mustafa, Kamal; Omar, Omar; Schliephake, Henning More authors...

Institutional repository: University of Zagreb School of Dental Medicine Repository

Cite this document

Sanz, M., Dahlin, C., Apatzidou, D., Artzi, Z., Božić, D., Calciolari, E. ... Schliephake, H. (2019). Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration. Journal of Clinical Periodontology, 46. (S21), 82-91. doi: 10.1111/jcpe.13123

Sanz, Mariano, et al. "Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration." Journal of Clinical Periodontology, vol. 46, no. S21, 2019, pp. 82-91. https://doi.org/10.1111/jcpe.13123

Sanz, Mariano, Christer Dahlin, Danae Apatzidou, Zvi Artzi, Darko Božić, Elena Calciolari, Hugo De Bruyn, et al. "Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration." Journal of Clinical Periodontology 46, no. S21 (2019): 82-91. https://doi.org/10.1111/jcpe.13123

Sanz, M., et al. (2019) 'Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration', Journal of Clinical Periodontology, 46(S21), pp. 82-91. doi: 10.1111/jcpe.13123

Sanz M, Dahlin C, Apatzidou D, Artzi Z, Božić D, Calciolari E, and sur.. Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration. Journal of Clinical Periodontology [Internet]. 2019 June 18 [cited 2024 November 26];46(S21):82-91. doi: 10.1111/jcpe.13123

M. Sanz, et al., "Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration", Journal of Clinical Periodontology, vol. 46, no. S21, pp. 82-91, June 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:738915. [Accessed: 26 November 2024]

Metadata
Title (english)Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration
AuthorMariano Sanz
AuthorChrister Dahlin
AuthorDanae Apatzidou
AuthorZvi Artzi
AuthorDarko Božić
AuthorElena Calciolari
AuthorHugo De Bruyn
AuthorHenrik Dommisch
AuthorNikos Donos
AuthorPeter Eickholz
AuthorJan E. Ellingsen
AuthorHåvard J. Haugen
AuthorDavid Herrera
AuthorFrance Lambert
AuthorPierre Layrolle
AuthorEduardo Montero
AuthorKamal Mustafa
AuthorOmar Omar
AuthorHenning Schliephake
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
Background and Aims: To review the regenerative technologies used in bone regeneration: bone grafts, barrier membranes, bioactive factors and cell therapies. Material and Methods: Four background review publications served to elaborate this consensus report. Results and Conclusions: Biomaterials used as bone grafts must meet specific requirements: biocompatibility, porosity, osteoconductivity, osteoinductivity, surface properties, biodegradability, mechanical properties, angiogenicity, handling and manufacturing processes. Currently used biomaterials have demonstrated advantages and limitations based on the fulfilment of these requirements. Similarly, membranes for guided bone regeneration (GBR) must fulfil specific properties and potential biological mechanisms to improve their clinical applicability. Pre-clinical and clinical studies have evaluated the added effect of bone morphogenetic proteins (mainly BMP-2) and autologous platelet concentrates (APCs) when used as bioactive agents to enhance bone regeneration. Three main approaches using cell therapies to enhance bone regeneration have been evaluated: (a) “minimally manipulated” whole tissue fractions; (b) ex vivo expanded “uncommitted” stem/progenitor cells; and (c) ex vivo expanded “committed” bone-/periosteum-derived cells. Based on the evidence from clinical trials, transplantation of cells, most commonly whole bone marrow aspirates (BMA) or bone marrow aspirate concentrations (BMAC), in combination with biomaterial scaffolds has demonstrated an additional effect in sinus augmentation and horizontal ridge augmentation, and comparable bone regeneration to autogenous bone in alveolar cleft repair.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Clinical Periodontology
Numberingvol. 46, no. S21, pp. 82-91
p-ISSN0303-6979
e-ISSN1600-051X
DOIhttps://doi.org/10.1111/jcpe.13123
URN:NBNurn:nbn:hr:127:738915
Publication2019-06-18
Document URLhttps://onlinelibrary.wiley.com/doi/10.1111/jcpe.13123
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-24 08:36:07