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Scientific paper - Original scientific paper
Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19
Life, 14 (2024), 10; 1267. https://doi.org/10.3390/life14101267
Jordan, Ana; Trkulja, Vladimir; Jurin, Ivana; Marević, Sanja; Đerek, Lovorka; Lukšić, Ivica; Manola, Šime; Lucijanić, Marko

Institutional repository: University of Zagreb School of Dental Medicine Repository

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Jordan, A., Trkulja, V., Jurin, I., Marević, S., Đerek, L., Lukšić, I. ... Lucijanić, M. (2024). Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19. Life, 14. (10). doi: 10.3390/life14101267

Jordan, Ana, et al. "Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19." Life, vol. 14, no. 10, 2024. https://doi.org/10.3390/life14101267

Jordan, Ana, Vladimir Trkulja, Ivana Jurin, Sanja Marević, Lovorka Đerek, Ivica Lukšić, Šime Manola and Marko Lucijanić. "Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19." Life 14, no. 10 (2024). https://doi.org/10.3390/life14101267

Jordan, A., et al. (2024) 'Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19', Life, 14(10). doi: 10.3390/life14101267

Jordan A, Trkulja V, Jurin I, Marević S, Đerek L, Lukšić I, and sur.. Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19. Life [Internet]. 2024 October 05 [cited 2024 November 23];14(10). doi: 10.3390/life14101267

A. Jordan, et al., "Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19", Life, vol. 14, no. 10, October 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:512097. [Accessed: 23 November 2024]

Metadata
Title (english)Accounting for Red Cell Distribution Width Improves Risk Stratification by Commonly Used Mortality/Deterioration Risk Scores in Adult Patients Hospitalized Due to COVID-19
AuthorAna Jordan
AuthorVladimir Trkulja
AuthorIvana Jurin
AuthorSanja Marević
AuthorLovorka Đerek
AuthorIvica Lukšić
AuthorŠime Manola
AuthorMarko Lucijanić
Author's institution(Dubrava University Hospital)
Author's institution(Sestre milosrdnice University Hospital Center)
Author's institutionUniversity of Zagreb
School of Medicine
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Higher red blood cell distribution width (RDW) levels have gained attention in the prognostication of many chronic metabolic and malignant diseases, as well as coronavirus disease 2019 (COVID-19). We aimed to evaluate whether accounting for RDW might contribute to risk stratification when added to commonly used risk scoring systems in adult COVID-19 patients. We retrospectively analyzed a cohort of 3212 non-critical COVID-19 patients hospitalized in a tertiary-level institution from March 2020 to June 2021. Admission RDW values were considered normal if they were ≤14.5% in males or ≤16.1% in females. The Modified Early Warning Score (MEWS), International Severe Acute Respiratory and Emerging Infections Consortium Coronavirus Clinical Characterisation Consortium score (ISARIC 4C), and Veterans Health Administration COVID-19 (VACO) index were evaluated as prognostic scores. RDW exceeded the upper limit in 628 (19.6%) of the patients. When RDW was accounted for, risks of the predicted outcomes were considerably different within the same MEWS, 4C score, and VACO index levels. The same patterns applied equally to patients who started, and those who did not start, remdesivir before deterioration. RDW may be a useful tool for stratifying risk when considered on top of commonly used prognostic scores in non-critical COVID-19 patients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleLife
Numberingvol. 14, no. 10, 1267
e-ISSN2075-1729
DOIhttps://doi.org/10.3390/life14101267
URN:NBNurn:nbn:hr:127:512097
Publication2024-10-05
Document URLhttps://www.mdpi.com/2075-1729/14/10/1267
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-11-11 12:18:04