Pain is, according to the definition of the International Association for the Study of Pain, an unpleasant, sensory and emotional experience connected to real or possible tissue damage or descriptively in terms of damage. Pain is the most expressed symptom of every clinical picture of oral cavity disease and the reason for the patient to contact his dentist. The feeling of pain is individual, difficult to compare and measure. Depending on the time of its occurence, pain can be acute or chronic. Acute pain is fast and sharp, it occurs during stimulus application or immediately after the stimulus has been removed. Chronic pain is dull, slow, it appears intermittently or continually, it can be dependent on the stimulus or spontaneous. It presents more character variations than the acute pain. Such patients often come to the dentist's office, complaining about the pain which is not present at that moment. This makes diagnostics harder and widens the spectrum of pathological changes which may cause such pain. Various dental surgeries can cause painful sensations of different character, intensities and duration. It is necessary to diagnose painful sensations and to remove the cause. Prosthetic therapy can cause physical pain in many clinical phases, however, physical pain is also connected to prosthetic rehabilitation due to disrupted chewing, phonetic and aesthetic function which is ensured by a healthy and sanitized stomatognathic system. The fear of uncertainty of functioning and aesthetics without prosthetic work during the therapy implementation and the fear and uncertainty of the new prosthetic work has great effect on the patient's behaviour. The 'new' smile changes the patient's facial appearance. One becomes aware of that and engages himself in conversation with others more confidently. Properly performed prosthetic therapy raises self-confidence of a patient and can open up new opportunities in life. This is achieved by a therapist who can correctly and individually indicate prosthetic work and recognize the personality of a patient and thus adapt the way of communication during therapy. A dentist should not fear painful sensations that a patient complains about, but using his knowledge make the correct diagnosis, recognise his possible mistake at work and as fast and as more efficiently as possible reduce the feeling of pain.