General anesthesia in pedodontics is a set of anesthesiology methods that try to perform favorable conditions for children/patient during dental procedures. The most common indications for general anesthesia are small and non-cooperable children, children who do not tolerate the use of local anesthetics, and children with disabilities in various chronological ages. Anesthesiology methods which will be applied are spread from minimal sedation to general anesthesia. Which type, and depth of anesthesia will be applied, primary depending on the dentistry procedure, the estimated duration of the procedure and the health condition of the child. General anesthesia types could be complete inhalation, using only inhaled anesthetics, full intravenous, using only intravenous anesthetics, and combined inhaled and intravenous anesthetics. When choosing a method, it is necessary to consider children’s anatomical and physiological differences in relation to adults. Before the make decision on anesthetic approach, it is necessary to take a detailed anamnesis and physical status of the child, with special attention on some special information regarding on the child's age. Before the beginning of general anesthesia, it is necessary to establish basic hemodynamic monitoring. Maintenance the airway functional during dental procedures, is necessary because of several reasons: trying to maintain spontaneous ventilation, type of endotracheal intubation (oro or nasotracheal), and the prevent aspiration. As the most dental procedures are performed in a day-case system, it is important to recover the patient, establish proper contact with the patient, and discharge him from the hospital at the same day.