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master's thesis
Stečeni poremećaji hemostaze u oralnoj kirurgiji
Zagreb: University of Zagreb, School of Dental Medicine, 2018. urn:nbn:hr:127:464269
Nižetić, Lina
University of Zagreb
School of Dental Medicine
Department of Oral Surgery

Institutional repository: University of Zagreb School of Dental Medicine Repository

Cite this document

Nižetić, L. (2018). Stečeni poremećaji hemostaze u oralnoj kirurgiji (Master's thesis). Zagreb: University of Zagreb, School of Dental Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:127:464269

Nižetić, Lina. "Stečeni poremećaji hemostaze u oralnoj kirurgiji." Master's thesis, University of Zagreb, School of Dental Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:127:464269

Nižetić, Lina. "Stečeni poremećaji hemostaze u oralnoj kirurgiji." Master's thesis, University of Zagreb, School of Dental Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:127:464269

Nižetić, L. (2018). 'Stečeni poremećaji hemostaze u oralnoj kirurgiji', Master's thesis, University of Zagreb, School of Dental Medicine, accessed 09 November 2024, https://urn.nsk.hr/urn:nbn:hr:127:464269

Nižetić L. Stečeni poremećaji hemostaze u oralnoj kirurgiji [Master's thesis]. Zagreb: University of Zagreb, School of Dental Medicine; 2018 [cited 2024 November 09] Available at: https://urn.nsk.hr/urn:nbn:hr:127:464269

L. Nižetić, "Stečeni poremećaji hemostaze u oralnoj kirurgiji", Master's thesis, University of Zagreb, School of Dental Medicine, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:127:464269

Metadata
TitleStečeni poremećaji hemostaze u oralnoj kirurgiji
Title (english)Acquired Hemostasis Disorders in Oral Surgery
AuthorLina Nižetić
MentorIvan Zajc (mentor)
Committee memberIvan Zajc (predsjednik povjerenstva)
Committee memberDomagoj Vražić (član povjerenstva)
Committee memberNada Galić (član povjerenstva)
GranterUniversity of Zagreb
School of Dental Medicine
(Department of Oral Surgery)
Zagreb
Defense date and country2018-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Surgery
Abstract
Hemostaza je složeni prirodni proces međusobno povezanih reakcija koje sudjeluju u zaustavljanju krvarenja. Svojim mehanizmom održava krv u tekućem stanju te sprječava prekomjeran gubitak krvi. Hemostazu čine 4 faze, a to su: faza krvnih žila, faza stvaranja trombocitnog čepa, faza zgrušavanja te faza fibrinolize. Kada je uravnoteženi proces hemostaze ugrožen, pojavljuje se sklonost prekomjernom krvarenju ili zgrušavanju krvi. Stečeni poremećaji hemostaze mogu zahvatiti bilo koju od 4 faze hemostaze, a njihove se kliničke slike razlikuju. Nastanku poremećaja pridonose metaboličke i upalne bolesti koje dovode do oštećenja stijenke krvnih žila. Nadalje, oštećenje koštane srži dovodi do neadekvatnog stvaranja trombocita, a povećana funkcija slezene do pojačanog razaranja i zadržavanja trombocita. Na fazu zgrušavanja utječu bolesti jetre, koja je važna u sintezi čimbenika zgrušavanja, te mnogobrojni lijekovi koji djeluju na proces zgrušavanja. Razna stanja mogu dovesti do komplikacija zbog ubrzane razgradnje ugruška te uzrokovati krvarenje, odnosno tromboemboliju pri izostanku fibrinolize.
Abstract (english)
Hemostasis is a complex natural process of interrelated reactions which cause bleeding to stop. Its mechanism preserves blood liquidity and prevents excessive blood loss. Hemostasis consists of four steps: vascular spasm, platelet plug formation, blood coagulation and clot dissolution (lysis). When the balance of hemostasis process is disturbed, excessive bleeding or blood clotting may occur. Acquired hemostasis disorders can affect any of these four steps and can develop various clinical features. Different metabolic and inflammatory diseases may affect the vascular spasm. Furthermore, bone marrow damage disables platelets formation, while splenic hyperfunction leads to platelet destruction and preservation. Since coagulation factors synthesis occurs in the liver, various liver diseases, as well as medications which control the coagulation process, affect the coagulation process. Premature clot degradation can cause excessive bleeding, while the absence of clot degradation leads to thromboembolism.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:127:464269
Study programmeTitle: dental medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) icon
Created on2019-01-08 10:46:10