The salivary glands are exocrine glands that produce saliva through a system of ducts. There are three pairs of major salivary glands in the mouth: parotid, submandibular and sublingual, and a large number of minor salivary glands, located in oral mucosa, in tongue, palate, retromolar triangle, pharynx, larynx and paranasal sinuses. Salivary gland tumors can occur in every major salivary gland as well as in minor salivary glands, they are rare and represent about 3% of tumors occuring in oral cavity. Approximately 85% arise in major salivary glands of which 90% in parotid gland and 10% in submadibular gland. Sublingual gland is very rarely affected. The remaining 15- 25% are located in minor salivary glands, most frequently in the palate. Unlike tumors of the major salivary glands which are benign in 85% of cases, almost half of the minor salivary gland tumors are malignant. The most common benign lesions are pleomorphic adenoma (mixed tumor) and Warthin's tumor (papillary cystadenoma lymphomatosum). The most common malignant salivary gland tumors are mucoepidermoid carcinoma, adeniod cystic carcinoma, acinic cell carcinoma, squamos cell carcinoma, and carcinoma ex pleomorphic adenoma. Diagnostics of salivary gland diseases includes examination of the patient, ultrasonography, magnetic resonance imaging, computed tomography, scintigraphy, sialography, fine-needle aspiration cytology, salivary gland biopsy and in the end pathohistological diagnosis. The treatment is exclusively surgical. In case of a long-term nontreatment, it can lead to malignant transformation and relapse if not removed completly.