Bone healing is a complex physiological process that involves the coordinated action of a number of cells and their precursors. Bone is a dynamic tissue composed of multiple metabolically active cells integrated into a rigid matrix which, unlike many other tissues that heal with a scar, is completely regenerated by equivalent bone tissue. Tooth replantation is a procedure by which a tooth returns to the alveolus after avulsion. Avulsion is the most severe form of dental trauma. Healing after replantation depends on the preservation of the periodontal ligament (PDL) of the avulsed tooth. In order for healing to be successful, it is crucial to preserve the vitality of PDL cells remaining at the root of the tooth. Tooth autotransplantation is a surgical repositioning of a tooth in the same person. It can also be defined as a controlled teeth avulsion and replantation into a new, surgically prepared alveolus. Healing after transplantation, as well as healing after replantation, depends on preserving the vitality of PDL cells on the surface of the root of the tooth. Implantation is a surgical procedure of placing a dental implant in the place of a lost tooth. The dental implant is a replacement made of alloplastic and biocompatible material which is surgically implanted in the jawbone in order to support the fixed orthe removable prosthetic devices. Modern dental implantology is based on the idea of osseointegration, i.e. it strives to create a direct connection between the bone and the implant without the inserted layers of soft tissues.