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master's thesis
Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini
Zagreb: University of Zagreb, School of Dental Medicine, 2015. urn:nbn:hr:127:974062
Kovačić, Ines
University of Zagreb
School of Dental Medicine
Department of Fixed Prosthodontics

Institutional repository: University of Zagreb School of Dental Medicine Repository

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Kovačić, I. (2015). Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini (Master's thesis). Zagreb: University of Zagreb, School of Dental Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:127:974062

Kovačić, Ines. "Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini." Master's thesis, University of Zagreb, School of Dental Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:127:974062

Kovačić, Ines. "Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini." Master's thesis, University of Zagreb, School of Dental Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:127:974062

Kovačić, I. (2015). 'Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini', Master's thesis, University of Zagreb, School of Dental Medicine, accessed 01 February 2025, https://urn.nsk.hr/urn:nbn:hr:127:974062

Kovačić I. Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini [Master's thesis]. Zagreb: University of Zagreb, School of Dental Medicine; 2015 [cited 2025 February 01] Available at: https://urn.nsk.hr/urn:nbn:hr:127:974062

I. Kovačić, "Polilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini", Master's thesis, University of Zagreb, School of Dental Medicine, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:127:974062

Metadata
TitlePolilaktična kiselina: Istraživanje vremena degradacije i mogućnosti primjene u rekonstruktivnoj dentalnoj medicini
Title (english)Polylactic acid: research of degradation time and possibilities of use in reconstructive dental medicine
AuthorInes Kovačić
MentorAmir Ćatić (mentor)
Committee memberAmir Ćatić
Committee memberBernard Janković
Committee memberMarko Jakovac
GranterUniversity of Zagreb
School of Dental Medicine
(Department of Fixed Prosthodontics)
Zagreb
Defense date and country2015-07-03, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Prosthetic Dentistry
Abstract
Zahtjevi današnjih pacijenata predstavljaju veliki izazov u rješavanju problema gubitka zubi. Kao prvi problem nameće se gubitak volumena i povoljne arhitekture alveolarne kosti koja je temelj za postizanje optimalne funkcionalne i estetske protetske rekonstrukcije u vidu klasične fiksnoprotetske ili implantoprotetske terapije. Najčešće upotrebljavana i najbolje dokumentirana metoda povećanja volumena kosti jest vođena regeneracija kosti (eng. guided bone regeneration, GBR) pri kojoj se upotrebljavaju koštani augmentati (autologni, ksenogeni, sintetski i alogeni) i membrana koja održava augmentacijski prostor. Cilj istraživanja jest utvrditi vrijeme raspada bioresorptivne membrane iz polilaktične kiseline te trajnost mehaničke izdržljivosti njezina oblika tijekom augmentacijskoga procesa. U istraživanju su upotrijebljeni Purasorb® PDLG 5010 (50/50 DL-actide/glycolide copolymer; Purac Biomaterials, Nizozemska) i Purasorb® PG S (Polyglycolide; Purac Biomaterials, Nizozemska). Izrađeni su uzorci veličine 2 x 5 x 20 mm, izmjerena je masa svakoga uzorka te je po šest uzoraka uronjeno u tri različite tekućine (fiziološku otopinu, umjetnu slinu i Ringerovu otopinu). Svakih sedam dana mijenjana je tekućina te izmjerena masa uzorcima. Nakon sedam dana u svim trima tekućinama uočen je mali porast mase svih uzoraka. Nakon 21 dana uzorci su izgubili svoj prvotni oblik i mehaničku čvrstoću. Usporedbom porasta mase u prvih četrnaest dana za sve tri tekućine uočen je približno jednak porast mase svih uzoraka (prosječno 0,011323g u 14 dana).
Abstract (english)
Tooth loss and the resulting alveolar bone resorption present a significant challenge in modern dentistry. First, the loss of bone volume and architecture significantly influences the possibilities of achieving optimal function and aesthetics, both relative to classic fixed prosthodontic therapy, but also implant-prosthodontics. The most widely used and documented method of bone augmentation is guided bone regeneration (GBR), in which bone augmentation grafts (autologous, xenograft, synthetic and allogeneic) and membranes are used. The aim of this study is to determine the degradation time of the bioresorbable polylactic acid membrane, and the durability of its mechanical properties during augmentation. Purasorb® PDLG 5010 (50/50 DL-lactide/glycolide copolymer ; Purac Biomaterials, The Netherlands) and Purasorb® PG S (Polyglycolide; Purac Biomaterials, The Netherlands) have been used in the study. Samples 2x5x20 mm in size were made, their mass was measured and six samples were immersed in each of the three different solutions (saline solution, artificial saliva and Ringer's solution). Every seven days the solutions were replaced with fresh ones, and the mass of the samples was measured. After 21 days, the samples lost their form and mechanical properties. A comparison of the mass gain of all saples from all three solutions after the first 14 days revealed that the mass gain of all of the samples was approximately the same (mean 0,011323g in 14 days).
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:127:974062
Study programmeTitle: dental medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) icon
Created on2016-04-04 09:25:28