Depression is a state of low mood and aversion to activity that can affect a person’s thoughts, behaviour, feelings and physical well-being which lasts minimum for 2 weeks. Depression is common and serious problem that often starts in childhood. Today is estimated that approximatly 10-15% of children in general population has syptoms of depression. It is associated with an increased risk of other psychiatric disorders, poor academic success, underdeveloped social skills and even suicidal thoughts. The primary symptoms of depression are continuous feelings of sadness and hopelessness and mood changes. Symptoms of depression in children also include irritability or anger, social withdrawal, changes in appetite (either increased or decreased), changes in sleep (sleeplessness or excessive sleep), difficulty concentrating, etc. Depressive disorders include Major depressive disorder, dysthymic disorder, depressive disorder, indeterminate and bipolar disorder. Depression in children can be caused by any combination of factors that relate to physical health, life events, family history, environment, genetic vulnerability and biochemical disturbance. Depression should be recognized and diagnosed as early as possible in children and adolescents in order to start treatment on time. The most efficient treatment is a treatment that is not focused on depressive symptoms only, but also on functioning on daily bases in children.