Physical exercise and sports enable the complete development of the child. They affect the activation of the locomotor system, which is crucial for the transformation of energy needed for the activity of all cells in the body. By exercising, a person acquires healthy habits for further life. Children participate in various forms of physical activity through play or sports. It is important to mention the role of preschool institutions and preschool teachers who promote physical activity, and thus the child's growth and development. A preschool teacher creates physical activities through a structure consisting of the introductory, preparatory, main and final part of the lesson. The aim of this paper is to investigate the impact of physical activity on children with disabilities, the benefits of physical movement for children and highlight the adjustments by which children with disabilities will be able to participate in the performance of motor tasks. Research in the literature has revealed many positive effects that sport and physical activity have on children with developmental disabilities. In addition to moving the child's body, physical movement increases muscle strength, improves coordination and balance, reduces the risk of obesity, improves dexterity, flexibility and elasticity. It also works on the psychic plane; the child feels better, creates a positive image of himself, and thus becomes more accepted in society and gains more self-esteem, which is extremely important. It has been established that physical activity in children with disabilities alleviates the consequences of the damage itself because it has a positive effect on the whole organism. Adaptation has been shown to be very important in conducting physical activities with children with developmental disabilities. It is of great importance that a preschool teacher provides the child with disabilities with support, understanding and the opportunity to be accepted by other children in the group, which is achieved by adapting the equipment, space, materials and methods of work. This way, a child with developmental disabilities will be able to perform motor tasks and participate in activities like other children.