Vaccination is considered to be one of the most important and high-quality health measures provided today in medicine as a measure aimed at preserving health rather than treating disease. In order for vaccination to be successful, it is necessary to maintain a high vaccination rate in order to prevent the return of eradicated diseases. Encouraged by the increasing spread of negative attitudes towards vaccination, I decided to conduct a study aimed at questioning parents about their attitudes and knowledge about mandatory vaccination of children. The study involved 100 respondents who were offered an anonymous online survey of 34 questions. The study included three hypotheses. The first hypothesis that most parents have a positive attitude towards vaccination has been confirmed and research has shown that most parents have a positive experience with vaccination. Most parents get information about vaccinations online and from doctors, and this confirms the second hypothesis set in the research. Most parents rate their information about vaccination as excellent and very good, and cite the fear of side effects as the reason for not vaccinating their children. The third hypothesis of the research has not been confirmed because the experience of other parents does not influence the decision to vaccinate most parents. It is important to maintain a positive attitude towards vaccination and to educate parents about the importance of vaccination in order to prevent the spread of a negative attitude.