A major problem in the preservation of cultural assets in urban areas is the contamination of the same with graffiti. For successful graffiti removal is necessary to identify the type of material and the type of paint with which the material is contaminated and know their chemical and physical properties in order to minimize the impact on the originality of the material with a potential paint removal method. The paper is divided into three parts. The first part describes the properties of materials that are most often contaminated with graffiti. The emphasis in the research has been placed on the stone of carbonate origin because it is the most common material contaminated with graffiti in Dalmatia, the geographical area in which this research was conducted. All this information has been collected for the purpose of continuing research that expanded to find information about the interaction of materials, paints used to make graffiti and potential methods for removing the same for the purpose of finding the most effective method for removing graffiti. In the second part, based on the research Photo-oxidative stability of paraloid acrylic protective polymers by O. Chiantore, M. Lazzari, in which it was proven that the interaction of UV radiation and acrylic paint breaks the bonds within the molecule, a test has been made in which the spray paint samples, which is also acrylic-based, have been exposed to UV radiation using a UV lamp with the expectation that the bonds within the paint molecule will begin to break and that the paint will be easier to remove. The samples have been taken by FT-IR after the action of UV radiation, and the images show the breaking of intermolecular bonds and partial removal of color, but the time interval of this method is not satisfactory. Since the UV cleaning method did not give satisfactory results in the third part, tests have been made to clean the graffiti-contaminated stone using available commercial coating removers in combination with already known cleaning methods. Most of the tests have been made on stone of local origin, and the tests have also been made on plaster which is also a material often exposed to graffiti. The obtained results could be applied by experts in order to shorten the time when choosing a suitable agent, the method of its application, the time interval of action, the method of cleaning and in the selection according to financial affordability. Such a solution would reduce the risk of damage to the material itself, because used commercial agents act only on the paint layer, but not on the material itself and its patina, which has been the case with previous methods suchas sandblasting. It would also reduce the cost of the graffiti removal process which is quite high for now due to the methods that require the use of various machines and their transport.