Pain is an unpleasant emotional experience linked with an instant or threatening tissue injury experience described in the context of that injury is the official definition of pain given by The International Association for the Study of Pain and accepted by The World Health Organization.Pain is the commonest problem that makes people visit their doctors as well as the most frequent symptom that indicates the beginning of illness or illness itself. Together with fear, pain is evolutionally the oldest reaction of organism to any attack or destruction. Pain is subjective feeling and thus it is not easy to measure it. As there are no two identical persons there are no two identical reactions to pain. The causes of pain may be psychological, physical, social and mental. It is hard to compare the biological pain with emotional, psychological or mental pain but nevertheless all the causes result in suffering. Pain presents dominant community health care problem in which the palliative care has an important significance and the role of a nurse is of a priceless value.The basic human right is the release of pain and suffering as no one should suffer in silence or die in pain. Modern science and clinical practice have provided considerate reduction of pain and suffering no matter aetiology and therefore the door to the development of contemporary palliative principles has been opened.