Colelithiasis is a gallbladder disease that today affects more and more populations in Croatia and in the world. Obesity is more prone to women because the female hormone estrogen affects the slowing down of juvenile juice stiffening. There are methods of natural methods that can help dissolve and eliminate gallstones, but sometimes the operation is the only solution. The general preoperative preparation of the patient, the immediate preparation of the day before surgery and on the day of surgery, and postoperative care were elaborated. Possible after-operational difficulties and complications have been considered. The nurses' tasks are also described in surgical surgeries. The importance of proper nutrition and health education has been emphasized after the operation of the cholelithiasis. Particular emphasis was placed on the role of the nurse in the process of treating and recovering the patient. Continuous nursing care for patients in gallbladder operation requires specific knowledge and skills of nurses to bring the patient back to their regular life activities and work. In this final work I will explain the complexity and the need for continuous nursing care for patients after cholecystectomy.