Despite the fact that nurses/technicians are first close contact with patients and users of health services on a daily basis, and are also co-responsible for the proper administration of pharmacotherapy, according to HALMED reports (if we exclude reports of vaccine side effects due to the SARS-CoV-2 viruspandemic), no significant increase is seen reporting of side effects to drugs, especially not by nurses/technicians although there is a legal obligation to report them (N.N. 76/2013, 90/14, 100/18 article 1 and 61). The analysis of the mentioned topic shows the opinion of nurses / technicians at the level of primary health care with an emphasis on the activity of family medicine and community nursing. These groups are most often included application and use of various types of drugs, and thus with possible their side effects. It is important to discuss about this topic, first of all due to the recognition of our profession in the process of reporting possible side effects, and then also because due to the fact that we are the first in communication with the patient, during which we take all the general information (from the complete pharmacotherapy, the basic diagnosis to the social status). In order to be able to educate the users of our services, it is necessary to work on our own education (in this case, recognizing possible side effects and reporting them knowing standard pharmacovigilance processes). The results of this thesis showed that the knowledge of reporting side effects of drugs among nurses/technicians is very good, that the youngest respondents and nurses/technicians with the shortest working experience in primary health care have the most knowledge about side effects of drugs. The assumptions that nurses/technicians do not report side effects because they are not sufficiently informed about the legal obligation to report it, and the assumption that nurses/technicians can influence the "visibility" of the profession in recognizing and reporting side effects of drugs by increasing their personal knowledge of pharmacovigilance have been confirmed.