Title Ciljana terapija u onkologiji - izazov u sestrinskoj profesiji
Title (english) Targeted therapy in oncology - a challenge in nursing profession
Author Ivana Lukić Franolić
Mentor Ivo Dumić-Čule (mentor)
Committee member Ivan Milas (predsjednik povjerenstva)
Committee member Ivo Dumić-Čule (član povjerenstva)
Committee member Ivana Živoder (član povjerenstva)
Granter University North (University centre Varaždin) (Department of Nursing) Koprivnica
Defense date and country 2022-10-18, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences
Abstract Rak je vodeći javnozdravstveni problem u Republici Hrvatskoj. Broj oboljelih od raka u svijetu i Republici Hrvatskoj u stalnom je porastu. Svjetska zdravstvena organizacija (SZO) predviđa da će broj novooboljelih u svijetu porasti s 18 milijuna u 2018. na 29,5 milijuna godišnje u 2040. godini, dok će broj umrlih porasti s 9,5 na 16,4 milijuna godišnje. Malignu onkologiju mnogi doživljavaju kao smrtnu kaznu, ali moderna medicina neprestano razvija nove metode liječenja, čak i najsloženijih bolesti poput raka.
Donedavno su istraživači i liječnici smatrali kako su svi karcinomi koji potječu od istog sijela biološki slični pa su bolest klasificirali na temelju tipa stanica (određenog mikroskopskom procjenom), veličine tumora i prisutnosti/odsutnosti zahvaćenosti lokalnih limfnih čvorova ili udaljenih metastaza, kao i drugih karakteristika koje su uočili na uzorku tumora. Sada je jasno da se tumori nastali u istom organu mogu razlikovati na više neobično važnih načina, iako su “stari” dijagnostički parametri i dalje ključni elementi za odluku o liječenju. Jedan korak naprijed predstavlja mogućnost klasifikacije tumora temeljem važnih molekularnih terapeutskih ciljeva, identificiranih unutar zadnjih desetak godina pomoću vrlo kvalitetnih translacijskih istraživanja. Ciljana terapija inovativan je pristup u borbi protiv raka, a pokazuje visoku stopu. Zahvaljujući ovoj metodi milijuni ljudi iz različitih zemalja uspjeli su izliječiti smrtnu bolest i vratiti se u cjelovit život.
Medicinske sestre suočavaju se sa sve većim izazovima i prilikama u komunikaciji, podršci i zagovaranju pacijenata s obzirom na dostupnost naprednog testiranja, skrbi i liječenja u personaliziranoj i preciznoj medicini.
Abstract (english) Cancer is the leading public health problem in the Republic of Croatia. The number of cancer patients in the world and in the Republic of Croatia is constantly increasing. The World Health Organization (WHO) predicts that the number of new cases worldwide will increase from 18 million in 2018 to 29.5 million annually in 2040, while the number of deaths will increase from 9.5 to 16.4 million annually. Malignant oncology is perceived by many as a death sentence, but modern medicine is constantly developing new treatment methods, even for more complex diseases such as cancer.
Until recently, researchers and doctors believed that all cancers originating from the same seed were biologically similar, so they classified the disease based on cell type (determined by microscopic evaluation), tumor size, and the presence/absence of local lymph node involvement or distant metastases, as well as other characteristics that were observed in the tumor sample. It is now clear that tumors originating in the same organ can differ in a number of unusually important ways, although the "old" diagnostic parameters are still key elements for the treatment decision. One step forward is the possibility of classifying tumors based on important molecular therapeutic targets, identified within the last ten years using high-quality translational research. Targeted therapy is an innovative approach in the fight against cancer, and it shows a high rate. Thanks to this method, millions of people from different countries managed to cure a fatal disease and return to a complete life.
Nurses face increasing challenges and opportunities in patient communication, support and advocacy given the availability of advanced testing, care and treatment in personalized and precision medicine.
Keywords
rak
ciljana terapija
medicinske sestre
Keywords (english)
cancer
targeted therapy
nurses
Language croatian
URN:NBN urn:nbn:hr:122:300591
Study programme Title: Nursing Study programme type: university Study level: graduate Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2023-03-06 15:27:58