Patient safety is a term that has recently started to be used for the reason that more and more unwanted events are appearing, and the level of warning and knowledge about preventing incidents is low. Working in a safe manner is crucial to deliver quality health care, therefore patient safety should be a part of nursing education at all levels. The value of how the processes work in the organization is defined as the safety culture. Today's expectations for health care are at a high level. Medicine is advancing technologically and scientifically, but the fact is that medical errors and unwanted events occur every day when working with patients. The main goal of this work is to investigate how newly employed nurses/technicians evaluate their own knowledge about patient safety. 109 respondents took part in this research. The validated HPEPSS questionnaire was used, which was translated from English and adapted. It consists of 28 questions. Socio-demographic data were collected, and then the questionnaire was divided into 6 domains of competence, within which there are questions related to a particular area. The results were processed using descriptive and inferential statistics using the SPSS program - Statistics for Windows. The outcome showed that there is a difference in the perception of knowledge about patient safety considering the gender of the respondents. The participants showed that difference in the knowledge about patient safety considering the age of the respondents is not significant. Older age the level of education did not affect the level of knowledge about patient safety. Considering the place of employment (hospitals, health centers, etc.), the research results show that in one's own knowledge about safety is not so significant. The level of knowledge about patient safety according to respondents does not depend on the length of work experience. Considering the equal knowledge of patient safety among all respondents, which is at an average level, the need to include the subject of patient safety in education in a more concrete way is highlighted.