Compressive syndromes or nerve compressions most often occur in places where the nerve passes through an anatomically narrow opening. They can also be caused by the protrusion of bone or cartilage into the cervical, thoracic or lumbar spinal canal and rupture of the intravertebral disc. Compression can be acute or chronic. Acute compressions are compressions that occur after prolonged pressure on the nerve. The symptoms are initially mild, such as paresthesias and tingling, and gradually worsen, leading to muscle weakness and complete loss of muscle function and permanent damage. Neuropathies are diseases of the peripheral nervous system that include sensory, motor and autonomic nerves and the glia that surround them. Characterization depends on the affected nerves, heredity and exposure to drugs or toxins. It is manifested by symptoms such as pain, tingling, redness, swelling, insensitivity, and muscle weakness and atrophy. Physical therapy is one of the very important factors in the treatment of compressive syndromes and neuropathies. With physical therapy, we can greatly speed up recovery, reduce symptoms and prevent the progression of the disease as much as possible. In order for physical therapy to be properly dosed and an appropriate plan created, it is first necessary to do a high-quality physiotherapy assessment. Regardless of whether it is compressive syndromes or neuropathy, an individual approach and a well-done physiotherapy assessment are required.