Title Uloga infekcije humanim papilomavirusom (HPV) u nastanku karcinoma vrata maternice
Title (english) The role of human papillomavirus (HPV) infection in the development of cervical cancer
Author Ivana Grčić
Mentor Tomislav Meštrović (mentor)
Committee member Ivana Živoder (predsjednik povjerenstva)
Committee member Tomislav Meštrović (član povjerenstva)
Committee member Sonja Obranić (član povjerenstva)
Granter University North (University centre Varaždin) (Department of Nursing) Koprivnica
Defense date and country 2024-07-15, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Infectology
Abstract Humani papiloma virus (HPV) je kompleksna skupina virusa povezanih s razvojem različitih epitelnih lezija i karcinoma, uključujući rak vrata maternice. Epidemiološka istraživanja ističu HPV kao najčešće spolno prenosivu infekciju u svijetu, s visokim rizikom od infekcije kod spolno aktivnih osoba. Različiti čimbenici rizika, poput seksualnih navika, pušenja i imunološkog statusa, doprinose nastanku HPV infekcije. Infekcija se prenosi prije svega seksualnim kontaktom, ali postoje i drugi, manje dokumentirani načini prijenosa. Klinička slika infekcije varira od asimptomatske do manifestacija genitalnih bradavica ili prekanceroznih lezija.
Dijagnoza HPV infekcije temelji se na različitim metodama testiranja, uključujući Pap test i HPV testiranje. Liječenje HPV infekcije je ograničeno, jer većina infekcija spontano regredira, ali kod nekih pacijenata može biti potrebna intervencija radi sprečavanja napredovanja u malignu bolest.
Uloga HPV infekcije u nastanku raka vrata maternice je dobro dokumentirana.
Visokorizični tipovi HPV, posebno HPV 16 i 18, identificirani su kao glavni uzročnici ovog oblika raka. Prevencija i rano otkrivanje raka vrata maternice ključni su u borbi protiv ove bolesti. Cijepljenje protiv HPV-a pokazalo se kao učinkovita mjera prevencije, pružajući zaštitu od određenih tipova HPV-a povezanih s rakom. PAPA test je važan dijagnostički alat koji omogućuje ranu detekciju prekanceroznih promjena na vratu maternice. Povezanost HPV-a s različitim zloćudnim bolestima, uključujući rak vrata maternice, ističe važnost razumijevanja i praćenja ove infekcije u prevenciji malignih tumora.
Nacionalni preventivni programi raka vrata maternice značajno doprinose prevenciji raka vrata maternice. Važna je i uloga medicinske sestre u edukaciji o prevenciji populacije, te promicanju cijepljenja kao najučinkovitije metode prevencije, ali i poticanje na redovne preglede.
Abstract (english) Human papillomavirus (HPV) is a complicated collection of viruses that cause a variety of epithelial lesions and malignancies, including cervical cancer. According to epidemiological study, HPV is the most frequent externally transmitted illness in the world, with persons who spend time outside being most vulnerable to infection. Several risk factors, including sexual practices, smoking, and immunological state, contribute to the development of HPV infection. The illness spreads predominantly through sexual contact, although there are additional, less established modes of transmission. The clinical picture of the infection might range from asymptomatic to the appearance of genital warts or precancerous lesions. HPV infection is diagnosed using a variety of diagnostic procedures, including Pap and HPV tests. Most HPV infections resolve on their own, thus treatment is modest; however, certain individuals may require intervention to avoid progression to cancer.
The significance of HPV infection in cervical cancer has been extensively recognized. High-risk HPV strains, particularly HPV 16 and 18, have been identified as the leading causes of this kind of cancer. The prevention and early identification of cervical cancer are critical in the battle against this illness. The HPV vaccination has been shown to be an effective cancer prevention method, guarding against particular types of HPV. The PAPA test is an important diagnostic method that enables for the early detection of precancerous cervix changes. The link between HPV and numerous cancers, including cervical cancer in the mother, emphasizes the need of recognizing and monitoring this infection in the prevention of malignant tumors.
National cervical cancer preventive initiatives provide a substantial contribution to the prevention of cervical cancer. Nurses play a vital role in population preventive education, advocating vaccination as the most effective means of prevention, and encouraging routine check-ups.
Keywords
humani papiloma virus
rak vrata maternice
uloga
Keywords (english)
human papilloma virus
cervical cancer
role
Language croatian
URN:NBN urn:nbn:hr:122:103322
Study programme Title: Nursing Study programme type: university Study level: graduate Academic / professional title: sveučilišni magistar/magistra sestrinstva (sveučilišni magistar/magistra sestrinstva)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2024-08-29 11:56:03