Schizophrenia is a mental disorder. Persons with symptoms of schizophreniacan’t differentiatewhat is real and what is not real, know how to think, and its social behavior and logical thinking are abnormal. Ill persons can’t manage their emotions, and their ability to communicate and decision-making is diminished. These persons need to be accommodated in socio-medical facilities that provide long-stay for psychiatric patients. Schizophrenia still can’t be completely cured but it can be controlled with appropriate medicines treatment. In the first part of the dissertation are described history of schizophrenia, epidemiology and etiology of schizophrenia, types of schizophrenia, and healing and health care, while research is second part of dissertation. Accomodation of people with different mental disorders in three social institutions is described in this dissertation. This social institutions are in the region of Istria and they are: Center for adults Motovunin Motovun, Center for adults „Vila Maria“ in Pula andCenter for adults „Sv. Nedelja“ in Nedešćina. Aim of this dissertation is to find out which nursing diagnosis and which nursing interventions are most commonly encountered in working with persons suffering from schizophrenia which are accommodated into centre for long-term care.