Topic of this thesis is the application of polymer materials, titanium and additive technologies for the replacement and repair of bone tissue. Throughout history, one can observe the gradual development of prosthetics from completely simple wooden prostheses to today's smart prostheses with the possibility of imitating the movements of a real limb and sensations. In order for foreign bodies to be incorporated into the human body or to be in long-term contact with it, certain norms must be respected. This thesis, studies bone tissue replacement in detail. The materials used in conntact with human body must meet extremely strict standards such as ISO-10993 in order to cause no harm. In order to get a clearer picture of the movement and structure of the human body, especially the skeleton, the thesis briefly describes the mentioned functions and presents the basics of anatomy. The thesis describes biocompatible materials: metals, polymers and ceramics. Special attention was paid to polymes. In thesis is mentioned titanium as a biocompatible material of the widest use and currently an indispensable part of prosthetics due to its unique properties, which are described in the paper in detail. Development of titanium and cobalt alloys application in additive methods is also described in thesis. Additive methods which use polymer materials to create models which are base for developing implants or prostheses are also described, as well as procedures for making temporary polymer implants. Described in detail are printers and materials used in the laboratory at the Technical University in Košice and examples of models and implants made in the laboratory using additive methods.