Atrial fibrillation is one of the most common cardiac arrhythmias and is manifested by irregular and rapid heartbeat. Atrial fibrillation can be caused by a number of factors, which can be divided into variable and immutable. Atrial fibrillation can generate too many electrical impulses that then propagate rapidly and disorganizedly through the atrioventricular node and cause ventricular arrhythmia. There are four forms of FA: paroxysmal, persistent, long-term and permanent. If atrial fibrillation does not resolve spontaneously, drug therapy or cardiac interventions such as ablation are recommended. The prevalence of this arrhythmia is predicted to be increasing. This type of cardiac arrhythmia most often requires hospitalization of patients, which greatly reduces their quality of life as they had before the diagnosis of the arrhythmia itself. It is very important to take a good medical history, make a physical examination and make an electrocardiogram. The finding of a 24-hour measurement of cardiac electrical activity is very important in patients with atrial fibrillation to be able to determine appropriate drug therapy. The role of the nurse is very important, which is manifested through the process of health care, which begins from the admission to the discharge of the patient.