Polytrauma is defined as the simultaneous occurrence of severe injury to two body regions, with one vitally endangering the patient’s life. The care of the polytraumatized patient begins with the outpatient emergency medical service at the scene of the accident and during transport, and continues at the nearest health facility. During the treatment and care of these people, various algorithms are used, the quality implementation of which reduces the probability of error and omission to the lowest possible level. It is useful to be guided by the ABCDE protocol, which includes rapid and comprehensive identification and resolution of life-threatening conditions. Taking care of a polytraumatized patient is done consciously, quickly and responsibly with a multidisciplinary approach. Anesthesia care for a polytraumatized patient requires and understanding of the background of the injury and an assessment of the severity of the injury using rating scales. Furthermore, the procedure of resuscitation, sedation, analgesia and relaxation, anesthesia before and during surgery, hemodynamic stabilization and post-anesthetic care form an important part of anesthesia care. The anesthesiology technician as a member of the anesthesiology team plays an important role during the care of the polytraumatized patient. His role is to set up an intravascular approach, apply prescribed therapy, assist the doctor in setting up a central venous catheter, establish the airway, check all anesthesia equipment before surgery, monitor patients vital signs and timely identify the side effects of drug. In order to take care of polytraumatized patients people in the best possible way, in addition to investing in equipment, it is necessary to implement continuous education of all the staff. Continuous renewal of knowledge, skills and teamwork contributes to the quality of care and reduction of mortality.