The aim of the paper was to investigate the occurrence and impact of the Spanish flu in the city of Split during 1918 and 1919. The registers of the deceased of parishes St. Cross, St. Peter and the Cathedral and the register of the dead of the Split State Hospital were used to determine and describe the occurrence of the Spanish flu in the city. With the help of the mentioned documents, data on the number of deaths and their gender and age were collected. Based on the collected data, a descriptive statistical analysis was performed. The first deaths from this disease appeared in early September 1918, but the peak of the epidemic was in October and November same year. The highest number of deaths was recorded in the parish of the St. Cross, and the lowest in the parish of Cathedral. Most of the dead were between the ages of 20 and 40. In addition, a more women died from the consequences of illness. The analysis of Novo doba newspaper confirmed that very little media space was devoted to the Spanish flu even though it caused a high mortality.