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master's thesis
Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2015. urn:nbn:hr:178:103561
Bruić, Ana
University of Zagreb
Faculty of Veterinary Medicine
Reproduction and Obstetrics Clinic

Institutional repository: Repository of Faculty of Veterinary Medicine

Cite this document

Bruić, A. (2015). Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:103561

Bruić, Ana. "Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:178:103561

Bruić, Ana. "Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:178:103561

Bruić, A. (2015). 'Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:178:103561

Bruić A. Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2015 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:178:103561

A. Bruić, "Dijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:178:103561

Metadata
TitleDijagnostika, liječenje i praćenje kobile s old maiden mare sindromom (sindrom senilnih promjena uzrokovanih prekasnim uvođenjem u rasplod) - prikaz slučaja
Title (english)Diagnostic, Treatment and Observation of Mare with Old Maiden Syndrome (Syndrome of Senile Changes Due Breeding at Old Age) - Case Report
AuthorAna Bruić
MentorNikica Prvanović Babić (mentor)
Committee memberIva Getz
Committee memberGoran Bačić
Committee memberNikica Prvanović Babić
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
(Reproduction and Obstetrics Clinic)
Zagreb
Defense date and country2015-07-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Veterinary Clinical Sciences
Abstract
Kobila pasmine hrvatski toplokrvnjak prvi put je uvedena u rasplod u svojoj 17. godini. Kobila je bez problema koncipirala i iznijela graviditet do termina. Dvije godine kasnije ponovno je pripuštena i ostaje gravidna. Kroz drugi graviditet je višekratno liječena zbog vaginitisa i sumnje na placentitis. Taj graviditet je završio teškim porodajem zbog nepravilnog habitusa glave i prednjih nogu ždrijebeta. Ždrijebe je ekstrahirano tek nakon fetotomije. Nakon teškog porodaja zaostao je kroničan endometritis zbog prodora imunosti, zbog fibroze i oštećenja cerviksa te zbog ulaska i kolonizacije maternice mikroorganizmima. Uzimajući u obzir dob kobile te navedeni nalaz, kobili je dijagnosticiran sindrom prekasnog uvođenja u rasplod. Sindrom prekasnog uvođenja u rasplod odnosi se na kobile koje su uvedene u rasplod u dobi starijoj od 12 godina i obuhvaća niz senilnih promjena na reproduktivnim organima koje dovode do raznih patoloških stanja koja onemogućuju koncepciju ili onemogućuju da kobila iznese graviditet do termina. Uzet je ispirak endometrija koji je poslan na bakteriološku pretragu. Izolirana je Klebsiella pneumoniae i hemolitički Streptococcus sp., a antibiogram je pokazao njihovu osjetljivost na amoksicilin+klavulonsku kiselinu, gentamicin i enrofloksacin. Stoga je maternica isprana sa 6l Ringer laktata, nakon čega je intrauterino apliciran antibiotik (amoksicilin+klavulonska kiselina) uz rektalnu masažu maternice i aplikaciju oksitocina. Mjesec dana nakon toga obavljen je ginekološki i ultrazvucni pregled zbog učestalog vaginalnog iscjetka i ustanovljeno je da je maternica bez sadržaja, ali je i dalje prisutan konformacijski vaginitis koji predstavlja opasnost za ascedentnu infekciju maternice. Prognoze vezane uz plodnost ove kobile su loše, a kako bi se povečale šanse da kobila koncipira i iznese graviditet do termina preporučljiv je zahvat po Caslicku kako bi se suzbio konformacijski vaginitis. Također preporučljivo je napraviti biopsiju endometrija te patohistološku pretragu kako bi se ustanovio stupanj degenerativnih i upalnih promjena na endometriju, koji bi ukazao kolike su stvarne šanse da kobila koncipira i iznese graviditet do termina.
Abstract (english)
A Croatian warmblood mare was bred for the first time at the age of 17. The mare had no trouble in conceiving and having her foal to the term. She was covered two years later and conceived again. During the second pregnancy she was treated for vaginitis and suspected placentitis. The pregnancy ended with difficult parturition due to abnormal foal position. The dead foal was extracted by fetotomy. The mare developed a chronic persistent endometritis due to cervix damage and fibrosation, microorganism ascendance and colonization of the uterus and immunosuppression. Taking into consideration the mare’s age and clinical findings, old maiden mare syndrome was diagnosed. The syndrome refers to mares over 12 years of age, bred for the first time. Moreover, it includes a series of senile changes of the reproductive organs, leading to various pathological conditions which prevent conception or carrying the foal to the term. Endometrial flushing was performed and samples were sent for bacteriological examination. Klebsiella pneumoniae and hemolytic Streptococcus sp. were isolated. The antibiogram showed their sensitivity to amoxicillin + clavulanate, gentamicin and enrofloxacin. Therefore, the uterus was washed with 6 liters of Ringer lactate, followed by intrauterine application of the antibiotic (amoxicillin + clavulanate) combined with rectal massage, lastly oxytocin was applied. One month after the treatment a gynecological and ultrasound examination was performed due to frequent vaginal discharge. Although the uterus was without content, a conformational vaginitis was present which represent a threat of ascending infection to the uterus. Fertility prognosis for this mare is poor. To increase the chance of conceiving and carrying out to the term, Caslick surgery is recommended due to conformational vaginitis. Biopsy and histopathologic examination of the endometrium are also advisable in order to determine the degree of degenerative changes and inflammation of the uterus. This would be the main indicator of prognosis for further breeding.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:103561
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2015-12-03 10:15:52