Lymphomas in dogs represent a group of neoplastic diseases that arise from the clonal expansion of cells of the lymphoid lineage in central or peripheral lymphatic tissues and can then spread to other tissues. Lymphomas are the most common tumors of hematopoietic system in dogs and as such they have great clinical significance in veterinary medicine. Diagnosis of lymphoma in dogs is carried out on the basis of various examinations such as cytological, histopathological, immunocytochemical and immunohistochemical examinations, and the use of molecular diagnostic methods. Despite the increasing focus of the scientific community on this area, the epidemiology of lymphoma in dogs is still insufficiently researched, especially in the Republic of Croatia, due to the various challenges that epidemiologists face in their scientific work in veterinary medicine. In this research, an analysis of available data on lymphoma diagnoses in dogs made at the Department of Veterinary Pathology of the Veterinary Faculty of the University of Zagreb between 2009 and 2021 was carried out. The distribution of dogs with lymphomas with regard to age, sex and breed purity is in accordance with the existing literature. By comparing the number of dogs of certain breeds with lymphoma and the number of dogs of the corresponding breeds in the Issa Vams Tec system, the predisposition of certain breeds to the development of lymphoma was assessed. Bullmastiff, Shar Pei and Samoyed showed a high predisposition according to these data, while Yorkshire terrier, West Scottish white terrier and Maltese showed a low predisposition. Complete diagnoses of lymphoma in dogs, according to the currently recommended classification systems, made at the Department of Veterinary Pathology were few, probably due to the owners' reluctance to pay for tests. For this reason, in further research on the epidemiology of canine lymphoma in the Republic of Croatia, the author recommends performing examination of the samples archived at the Department of Veterinary Pathology.