Our study included 22 dogs, 12 males and 10 females, the retrospective review of medical records of Clinic for internal diseases has revealed they were diagnosed with anticoagulant poisoning through history, clinical examination, roentgenological findings and coagulation tests (PT and APTT). The most common main symptom of the poisoning was bleeding and it was found in 59% of dogs. 18% of dogs had dyspnea, while convulsions and inappetence were present in 9% of cases and depression in 5 % of animals. In 59% of dogs the temperature, heart rate and respiration rate were increased, while in 7% of dogs the values of heart rate and respiration rate were increased but the temperature was within normal limits. In 9% of dogs the temperature, heart rate and respiration rate were within physiological values. Statistically processed results of the roentgenological findings have shown that liquidothorax was found in 50% and liquidoperitoneum in 18% of animals, while hydropericard was found in 9 % of dogs. In 23% of cases roentgenological findings were negative. After the aspiration, haemothorax was confirmed in dogs with liquidothorax, haemoperitoneum in dogs with liquidoperitoneum and haemopericard in dogs with hydropericard. Comparing the results of haematological tests with physiological values, the mean value of the number of erythrocytes and the mean value of hematocrit were below physiological values, while the mean value of the number of thrombocytes was within the physiological values. The results of biochemical tests have shown that the mean value of urea was above and the mean value of creatinine was within normal limits. The mean values of total proteins and albumins were slightly below lower physiological limit and the mean value of creatinin phosphokinase was extremely above phisiological limits.