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master's thesis
DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2023. urn:nbn:hr:178:339533
Hobar, Stipe
University of Zagreb
Faculty of Veterinary Medicine

Institutional repository: Repository of Faculty of Veterinary Medicine

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Hobar, S. (2023). DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:339533

Hobar, Stipe. "DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:178:339533

Hobar, Stipe. "DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:178:339533

Hobar, S. (2023). 'DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:178:339533

Hobar S. DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2023 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:178:339533

S. Hobar, "DOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:178:339533

Metadata
TitleDOSADAŠNJE SPOZNAJE O POVEZANOSTI REŽIMA PREHRANE I POJAVE DILATATIVNE KARDIOMIOPATIJE (DCM) KOD PASA
Title (english)CURRENT KNOWLEDGE OF DIET REGIMEN AND DEVELOPMENT OF DILATATIVE CARDIOMYOPATHY (DCM) IN DOGS
AuthorStipe Hobar
MentorHrvoje Valpotić (mentor)
Committee memberDiana Brozić (predsjednik povjerenstva)
Committee memberTomislav Mašek (član povjerenstva)
Committee memberHrvoje Valpotić (član povjerenstva)
Committee memberŽeljko Mikulec (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
Zagreb
Defense date and country2023-07, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Animal Production and Biotechnology
Abstract
Nastanak dilatativne kardiomiopatije (DCM) se posljednjih 5 godina sve više povezuje s režimom prehrane koji u sebi sadrži mahunarke i krumpir. Glavnim čimbenikom te poveznice smatra se deficit taurina, nesencijalne aminokiseline koja sadrži sumpor i koju psi mogu endogeno sintetizirati. U namirnicama poput graška, leće, slanutka, količina prekursora taurina, aminokiselina metionina i cisteina, nije dovoljna, te posljedično tome može doći do deficita taurina i moguće pojave dilatativne kardiomiopatije. U velikih i gigantskih pasmina pasa, zbog smanjene sinteze taurina preporučuje se njegova suplementacija. Također deficiti nutrijenata poput karnitina, vitamina E, selena bakra, tiamina, ali i konzumacija hrane s visokim udjelom vlakana se povezuju s mogućim nastankom nutritivnog oblika DCM-a. Prema analizi Američke agencije za hranu i lijekove (FDA) velika većina pasa oboljelih od DCM-a konzumirala je suhu hranu koja u sebi nije sadržavala žitarice, a sadržavala je grašak i leću, što nam ukazuje na moguću poveznicu između pojedinih prehrana i nastanka DCM-a. Brojnim istraživanjima, u kojima se promjenom režima hranidbe u životinja oboljelih od DCM-a s netradicionalnog u tradicionalni, utvrdila su se poboljšanja u ehokardiografskom prikazu srca i sistoličkoj funkciji srca, smanjenju koncentracije srčanih biomarkera u krvi, te produženom srednjem vremenu preživljavanja. Zbog aktualnosti ove teme potrebna su daljnja istražvanja kako bi sa sigurnošću mogli povezati ove režime prehrane s nastankom DCM-a.
Abstract (english)
Development of dilatative cardimyopathy (DCM) in the last 5 years has been more and more connected with the diet regimen that contains pulse ingredients and potatoes. Main factor of that connection was taurine deficiency, dispensable sulfur-containing amino acid that can be endogenously synthesized in the dogs liver. Ingredients like peas, lentils, chickpeas do not contain sufficient amount of amino acids methionine and cysteine, precursors of taurine Consequence of that could be taurine deficiency and development of dilatative cardiomyopathy In big and giant dog breeds supplementation of taurine should be recommended as the taurine synthesis in these dogs is much lower. Deficiency in nutrients such as carnitine, vitamin E selenium, tiamine or consumation of high fibre diet could also be connected with diet induced DCM. According to the FDA analysis most of the dogs with DCM were fed with dry food tha was grain free and contained peas and lentils, which could indicate the connection between different diets and development of DCM. Numerous studies were made in which the positive effects of diet change from nontraditional to traditional on echocardiographic assesment and systolic function of the heart, alongside improvement of concentration of cardiac biomarkers in blood and median survival rate were observed. Because this is currently a new topic, more studies are necessary if we want to get more understading of connection between diet regimen and development of DCM.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:339533
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-07-20 08:45:23