A cat's pregnancy lasts 63 to 65 days. Cat is an induced ovulator and the release of luteinizing hormone and the subsequent ovulation occur triggered by coitus. Disturbances in various aspects of the pregnancy can cause early embryonic mortality and resorption, fetal death and abortion, and stillbirth. Most abortions are of infectious etiology. Bacterial infections can rarely be confirmed with certainty as the cause of abortion, on the contrary, retroviruses such as feline leukemia virus, feline immunodeficiency virus and the parvovirus are often encountered in the diagnosis of abortion. Losses caused by the parasite Toxoplasma gondii are the result of a systemic disease of the mother. Physiological aspects of newborn immaturity contribute to heavy losses during the neonatal period. Bacteria such as Staphylococcus spp., Streptococcus spp., Escherichia coli, Salmonella spp. and the parasite Toxocara cati are just some of the causative agents that represent a significant problem in neonatal kittens. When diagnosing the cause of pregnancy loss in animals, the placenta contains key clues and evidence. A significant challenge for the success of diagnostics is the time that has passed between sample collection, processing and sending to diagnostic centers. As this interval increases, tissues undergo autolysis, and pathogens may become more demanding or impossible to culture. In order to overcome these problems, veterinarians are encouraged to conduct a thorough necropsy, rapidly collect and process specimens, and use special transport media.