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master's thesis
Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2016. urn:nbn:hr:178:434653
Šelimber, Maja
University of Zagreb
Faculty of Veterinary Medicine
Department of Microbiology and Infectious Diseases with Clinic

Institutional repository: Repository of Faculty of Veterinary Medicine

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Šelimber, M. (2016). Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:434653

Šelimber, Maja. "Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:178:434653

Šelimber, Maja. "Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:178:434653

Šelimber, M. (2016). 'Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 02 December 2024, https://urn.nsk.hr/urn:nbn:hr:178:434653

Šelimber M. Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2016 [cited 2024 December 02] Available at: https://urn.nsk.hr/urn:nbn:hr:178:434653

M. Šelimber, "Seroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:178:434653

Metadata
TitleSeroprevalencija infekcije virusom influence A u pasa i mačaka na području sjeverozapadne i središnje Hrvatske
Title (english)The Seroprevalence of Influenza A Viral Infection in Dogs and Cats in the Northwestern and Central Croatia
AuthorMaja Šelimber
MentorLjubo Barbić (mentor)
Committee memberZoran Milas (predsjednik povjerenstva)
Committee memberSuzana Hađina (član povjerenstva)
Committee memberLjubo Barbić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
(Department of Microbiology and Infectious Diseases with Clinic)
Zagreb
Defense date and country2016-02-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Veterinary Clinical Sciences
Abstract
Influenca domaćih mesojeda je akutna, virusna, kontagiozna, respiratorna bolest koju uzrokuju različiti podtipovi virusa influence A iz porodice Ortomyxoviridae. Virus se širi izravnim dodirom s bolesnim životinjama, ali i zrakom te kontaminiranim predmetima, prostorom ili preko hrane. Infekcije najčešće prolaze subklinički ili su simptomi tek blagi i prolazni karakterizirani respiratornim sindromom koji uključuje umjerenu groznicu i kašalj. Međutim opisane su i infekcije s letalnim ishodom. U ovom istraživanju je po prvi put istražena proširenost infekcije virusom influence tip A u domaćih mesojeda kućnih ljubimaca s područja središnje i sjeverozapadne Hrvatske. U tu svrhu pretraženo je ukupno 628 uzoraka seruma od kojih 555 uzoraka seruma pasa i 73 uzorka seruma mačaka komercijalnim kompetitivnim imunoenzimnim testom (ID Screen® Influenza A Antibody Competition Multi-species). Specifična protutijela za nukleoprotein virusa influence A ustanovljena su u serumima ukupno šest životinja tako da je ukupna seroprevalencija 1%. Prema vrsti životinja seroprevalencija u pasa iznosila je 0,9%, a u mačaka 1,4%. Nisu ustanovljene epizootiološke poveznice između pozitivnih životinja kao niti klinički znakovi koja bi odgovarala infekciji virusom influence tip A. Bez obzira na relativno mali broj pozitivnih životinja, prvi dokaz infekcija domaćih mesojeda virusom influence tip A na području Republike Hrvatske ima iznimni značaj za svakodnevni klinički rad doktora veterinarske medicine jer očito i na našem području postoji opasnost od oboljenja domaćih mesojeda od influence. Još značajnije, dokaz infekcija kućnih ljubimaca virusom influence tijekom sezone influence u ljudi zasigurno predstavlja važnu smjernicu za javno zdravstvo te zahtjeva daljnja istraživanja radi određivanja uloge i značaja kućnih ljubimaca u širenju bolesti na ljude.
Abstract (english)
Influenza of domestic carnivores is acute, viral, contagious disease caused by different subtypes of influenza A virus member of Orthomyxoviridae family. The virus is transmitted by direct contact with sick animals, fomites, trough aerosol and contaminated food. Infections in domestic carnivores in majority of cases causes subclinical or with mild symptoms characterized by respiratory syndrome which include fever and cough. However, there have been described infections with lethal outcome. The aim of this study was to investigate the presence and prevalence of influenza A virus infection in domestic carnivores in central and north-west Croatia for the first time. A total of 628 domestic carnivore sera samples were tested by commercial competitive ELISA test (ID Screen® Influenza A Antibody Competition Multi-species). Out of 555 dog sera samples and 73 cat sera samples specific antibodies for influenza A nucleoprotein were detected in sera of six animals,. The overall seroprevalence was 1% and seroprevalence in dogs was 0,9%, and in cats 1,4%. There was no correlation of epizootilogical data between positive animals and even more positive animals had no clinical history of respiratory disease. Despite the relatively low number of positive samples, the first evidence of influenza virus A infections of carnivores in Croatia has clinical importance for routine practice because obviously in our field there is substantial risk of clinically overt influenza infections in domestic carnivores. Even more evidence of influenza infections in pet animals during the influenza season in people certainly highlights importance of pet animals in public health and require further research to determine their importance in spreading of the disease to people.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:434653
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2016-02-16 14:09:05