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master's thesis
Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2016. urn:nbn:hr:178:031338
Jakšić, Leo
University of Zagreb
Faculty of Veterinary Medicine
Department of Poultry Diseases with Clinic

Institutional repository: Repository of Faculty of Veterinary Medicine

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Jakšić, L. (2016). Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:031338

Jakšić, Leo. "Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:178:031338

Jakšić, Leo. "Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:178:031338

Jakšić, L. (2016). 'Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 25 January 2025, https://urn.nsk.hr/urn:nbn:hr:178:031338

Jakšić L. Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2016 [cited 2025 January 25] Available at: https://urn.nsk.hr/urn:nbn:hr:178:031338

L. Jakšić, "Karakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:178:031338

Metadata
TitleKarakterizacija poliklonskih antitijela IgY iz kokošjih jaja za protein CA 15-3 te njihova specifičnost za homologni protein u serumu kuja
Title (english)Characterisation of Polyclonal IgY Chicken Egg Antibodies for CA 15-3 Protein and Its Specificity for Homologous Protein in Bitch Serum
AuthorLeo Jakšić
MentorŽeljko Gottstein (mentor)
MentorDubravko Pavoković (mentor)
Committee memberDanijela Horvatek Tomić (predsjednik povjerenstva)
Committee memberDubravko Pavoković (član povjerenstva)
Committee memberŽeljko Gottstein (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
(Department of Poultry Diseases with Clinic)
Zagreb
Defense date and country2016-11-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Abstract
Neoplazije u pasa uzrokuju preko 50% uginuća u dobi iznad 10 godina, a najčešća u ženki pasa je neoplazija mliječne žlijezde, koja se može javiti već u dobi od 4 godine. Osim benignih, lokaliziranih oblika ove bolesti, u čak 80% slučajeva može se javiti u malignom obliku s metastazama po organizmu. Mogućnost pravovremene terapije u slučaju neoplazije mliječne žlijezde danas pridonosi izlječenju ili značajnom produženju života oboljelog psa kao i boljim uvjetima života, pa je rana dijagnostika iznimno važna. Tumorski marker iz seruma, CA 15-3, nedavno preuzet iz humane medicine gdje je korišten u dijagnostici raka dojke u žena, i u pasa se pokazao obečavajućim. Cilj diplomskog rada je istražiti kvalitetu poliklonskih anti-CA 15-3 IgY antitijela iz kokošjih jaja i njihovu specifičnost za tumorski marker u serumu kuja.
Abstract (english)
Neoplasia in dogs cause over 50% deaths at the age over 10 years, and the most common form in female dogs is the mammary gland tumor, which can appear as soon as at 4 years of age. Aside from benign, localised forms of this disease, a malignant, metastatic form may appear in as much as 80% of cases. Application of therapy at the right time in case of a mammary gland neoplasia contributes to the healing or the distinct increase of life expectancy of a diseased dog, as well as contributes to a finer conditions of life, therefore early diagnosis is of extreme importance. A serum-extracted tumor marker, CA 15-3, which has recently been adopted from the fields of human medicine, has been used in breast cancer diagnostics, and has shown great promise in dogs as well. The aim of this research is to investigate the quality of policlonal anti-CA 15-3 IgY antibodies extracted out of chiken eggs, and their specificity for the tumor marker in female dog serum.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:031338
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-07-23 10:36:09