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master's thesis
Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2018. urn:nbn:hr:178:777610
Magaš, Tea
University of Zagreb
Faculty of Veterinary Medicine
Reproduction and Obstetrics Clinic

Institutional repository: Repository of Faculty of Veterinary Medicine

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Magaš, T. (2018). Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:777610

Magaš, Tea. "Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:178:777610

Magaš, Tea. "Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:178:777610

Magaš, T. (2018). 'Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:178:777610

Magaš T. Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2018 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:178:777610

T. Magaš, "Primjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:178:777610

Metadata
TitlePrimjena testosterona u domaćih životinja - terapeutsko i anaboličko djelovanje
Title (english)The Use of Testosterone in Domestic Animals - Therapeutic and Anabolic Activities
AuthorTea Magaš
MentorMarko Samardžija (mentor)
MentorJelka Pleadin (mentor)
Committee memberIvan Folnožić (predsjednik povjerenstva)
Committee memberMarko Samardžija (član povjerenstva)
Committee memberJelka Pleadin (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
(Reproduction and Obstetrics Clinic)
Zagreb
Defense date and country2018-01-23, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Abstract
Spolni hormoni poput testosterona su tvari koje sintetiziraju spolne žlijezde. Riječ je o tvarima koje su uključene u endokrinu regulaciju rasta, kao i u razvoj spolnih karakteristika, kako u životinjskom, tako i u ljudskom organizmu. Postoje četiri skupine spolnih hormona i to androgeni, estrogeni, gestageni te relaksini. Cilj ovog rada je dati pregled literature o uporabi spolnih hormona u terapijske i anaboličke svrhe, s naglaskom na testosteronu. Naime, testosteron je najvažniji prirodni androgen koji se izlučuje u testisima te stimulira razvoj muških spolnih žlijezda te spolnih karakteristika. Najčešće se koristi u kombinaciji sa 17β-estradiolom. U radu se posebno ističe negativno djelovanje testosterona koji pri medicinski neopravdanoj uporabi može prouzročiti i mutacije gena te pojavu tumora. Spolni hormoni imaju čitav niz vrlo bitnih funkcija u organizmu. Osim na razvoj spolnih karakteristika, spolni hormoni mogu utjecati i na još nekoliko bitnih segmenata, poput rasta, te se stoga upotrebljavaju u terapijske i anaboličke svrhe. Što se tiče uporabe u terapijske svrhe, navedeni se hormoni s naglaskom na testosteron mogu opravdano koristiti kako bi se prevenirali i smanjili zdravstveni problemi u reproduktivnom sustavu. S druge strane neprimjerena uporaba spolnih hormona za poboljšanje rasta u cilju ostvarivanja financijske dobiti, odnosno u anaboličke svrhe, nije legalna s obzirom da mogu negativno djelovati ne samo na životinju, nego i na čovjeka kao konzumenta hrane životinjskog podrijetla. Slijedom toga, u proizvodnji konzumnih životinja zakonom je regulirana uporaba spolnih hormona, uključujući i testosteron. Osim nadležnih tijela, vrlo bitnu ulogu u nadzoru ovih tvari, imaju i veterinarske službe te kontrolni laboratoriji. U budućnosti je potrebno pronaći alternativna rješenja za terapijsku primjenu hormona u farmskih životinja, a sustavi kontrole trebaju biti još učinkovitiji, čime bi se isključila mogućnost zlouporabe ovih tvari u anaboličke svrhe.
Abstract (english)
Sex hormones such as testosterone are substances that synthesize the sexual glands. It is about substances that are involved in endocrine regulation of growth, as well as on the development of sexual characteristics both in animal and human organism. There are four groups of sex hormones, androgens, estrogens, gestagens and relaxants. The aim of this paper is to review the literature on the use of sex hormones for therapeutic and anabolic purpose with an emphasis on testosterone. Specifically, testosterone is the most important natural androgen excreted in the testicles and stimulates the development of male sex glands and sexual characteristics. It is most commonly used in combination with 17β-estradiol. In this paper the negative effect of testosterone is particularly emphasized, which can cause genetic mutations and the appearance of tumors in medical unjustified use. Sex hormones have a number of very important functions in organism. Apart from the development of sexual characteristics, sex hormones may also affect several other important segments such as growth and are used for therapeutic and anabolic purposes. As far as therapeutic use is concerned, these testosterone-specific hormones can be used to prevent and reduce health problems in the reproductive system. On the other hand, inadequate use of sex hormones to improve growth to achieve financial gain or anabolic purposes is not legal since they can have a negative effect not only on the animal but on the human as a consumer food of animal origin. Consequently, the law regulates the use of sex hormones including testosterone. In addition to the competent authorities, veterinary services and control laboratories have a very important role in the control of these substances. In the future, alternative solutions for therapeutic use of hormones in farm animals need to be found, and control systems should be more effective, thus excluding the possibility of abusing these substances for anabolic purposes.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:777610
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-07-24 10:44:19