Tetanus is an infectious disease in dogs caused by the tetanus toxin produced by bacterium C. tetani. The disease is more likely to occur in younger, male, large breed dogs. Portals of entry are various injuries, most commonly paw wounds contaminated with soil or feces. The incubation period of the disease ranges from three days up to three weeks. The clinical presentation of the disease is manifested in localized and generalized form. In the localized form of the disease, it will be visible rigidity of the limb on which the injury or wound is located. Generalized form is manifested by typical clinical symptoms, the most common of which are facial muscle spasm and stiff gait due to the pronounced stiffness of the extensor muscles and intermittent tonic spasms of the respiratory musculature. The disease is accompanied by a number of complications and the lethal outcome is the result of respiratory arrest or disorders of the cardiovascular system, with consequent cardiac arrest. Diagnosis is based on a detailed history and a typical clinical presentation. Treatment is long-term with the aim of neutralizing the free toxin, preventing further multiplication of bacterium C. tetani by antimicrobial medications and supportive therapy to treat symptoms. The prognosis and survival rate depends on the form and course of the disease. If the disease is recognized in time and adequately treated, it amounts to up to 90% survival rate. Recovery time varies and depends on the severity of the clinical presentation. Animals usually recover completely within four weeks without lasting neurological consequences. Immunoprophylaxis of tetanus in dogs is not carried out and the prevention of the disease is based on appropriate wound treatment and rational use of antimicrobial medications.