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master's thesis
Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma
Zagreb: University of Zagreb, Faculty of Veterinary Medicine, 2014. urn:nbn:hr:178:939977
Bosnić, Maša
University of Zagreb
Faculty of Veterinary Medicine
Department of Veterinary Pathology

Institutional repository: Repository of Faculty of Veterinary Medicine

Cite this document

Bosnić, M. (2014). Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma (Master's thesis). Zagreb: University of Zagreb, Faculty of Veterinary Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:178:939977

Bosnić, Maša. "Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:178:939977

Bosnić, Maša. "Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma." Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:178:939977

Bosnić, M. (2014). 'Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma', Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, accessed 04 January 2025, https://urn.nsk.hr/urn:nbn:hr:178:939977

Bosnić M. Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma [Master's thesis]. Zagreb: University of Zagreb, Faculty of Veterinary Medicine; 2014 [cited 2025 January 04] Available at: https://urn.nsk.hr/urn:nbn:hr:178:939977

M. Bosnić, "Dijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma", Master's thesis, University of Zagreb, Faculty of Veterinary Medicine, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:178:939977

Metadata
TitleDijagnostički pristup stadima paške ovce zaraženima jaagsiekte sheep retrovirusom uzročnikom plućnog adenokarcinoma
Title (english)Diagnostic Approach to the Paška ovca Herds Infected with Jaagsiekte Sheep Retrovirus Couse of Ovine Pulmonary Adenocarcinoma
AuthorMaša Bosnić
MentorAna Beck (mentor)
MentorAntun Kostelić (mentor)
Committee memberMarko Hohšteter
Committee memberAna Beck
Committee memberAntun Kostelić
GranterUniversity of Zagreb
Faculty of Veterinary Medicine
(Department of Veterinary Pathology)
Zagreb
Defense date and country2014-11-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Veterinary Medicine
Animal Production and Biotechnology
Abstract
Ovcji plucni adenokarcinom je transmisivni plucni tumor ovaca uzrokovan jaagsiekte sheep retrovirusom. JSRV inducira neoplasticnu transformaciju alveolarnog i bronhijalnog epitela, što rezultira okupacijom plucnog parenhima tumorskim masama. Inkubacija je duga i ovca u tom periodu izlucuje virus u okoliš, sve dok masa tumora ne naraste do dimenzija koje ovcu uguše. Postupcima oplemenjivanja genoma paške ovce JSRV je unesen na Pag i danas predstavlja enzootsko podrucje ove bolesti u Hrvatskoj. Prvi molekularni dokaz virusa iz tkiva adenokarcinoma, te prevalencija uginuca od 1 do 8 % , takoder upucuju da JSRV vec duže vrijeme perzistira na Pagu. Temeljem patoanatomske i histopatološke pretrage možemo zakljuciti da Paška ovca, kao i vecina svjetskih pasmina, boluje od klasicnog oblika OPA. Bolje upoznavanje veterinara i ovcara s problematikom vezanom uz ovu bolest jedini je nacin uspostave kontrole i sustavnog nadzora OPA-e u našoj zemlji.
Abstract (english)
Ovine pulmonary adenocarcinoma is a transmissible lung tumor of sheep, caused by jaagsiekte sheep retrovirus. JSRV induces neoplastic transformation of alveolar and bronchial epithelial cells, resulting in the occupation of the lung parenchyma by tumor masses. Incubation period is long and during this period sheep excretes virus in the environment, until the tumor mass grows big enough to suffocate the sheep. JSRV has infected the island of Pag during the breeding improvement programs and Pag today represents an enzootic area of this disease in Croatia. The first molecular evidence of the virus isolated from the adenocarcinoma tissue and mortality prevalence in the range of 1 to 8% also indicate that JSRV persisted on island of Pag for a longer period of time. Based on pathoanatomic and histopathological examinations sheep from Pag, like most of the sheep breeds in the world, suffer from the clasicall form of OPA. Better educational program for veterinarians and sheep farmers is the only way to establish control of this desease in our country.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:178:939977
Study programmeTitle: Veterinary Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica veterinarske medicine (doktor/doktorica veterinarske medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2015-12-03 09:34:51