Electromagnetic radiation is emitted from the natural environment, as well as through the use of industrial and everyday devices for wireless communication, and in that way are constantly exposed human and animal organisms. Over the recent years, due to rapid technological progress, Electromagnetic radiation from artificial sources has exceeded the values of radiation of natural origin. General concern about the increasing number of devices (mobile phones, laptops, Wi-Fi and microwave ovens), which use radio frequency / microwave radiation is justified due to the increasing number of evidence of their harm to the living organism. Modern devices of modern technology emit radio frequency electromagnetic waves of small frequencies which are then absorbed by the human and animal bodies and can have potential adverse effects on the brain, heart, endocrine system and reproductive function. It is believed that the male reproductive system is one of the most sensitive tissues on electromagnetic radiation. For example, it is clear from currently available studies that radio frequency electromagnetic fields have harmful effects on ejaculate quality indicators (such as spermatozoa count in ejaculate and spermatozoa morphology and motility), affect cellular metabolism and endocrine system and cause genotoxicity, genomic instability and oxidative stress, which may cause infertility. The adverse effects of radiofrequency electromagnetic waves are divided into thermal and non-thermal. Most of the negative biological effects are attributed to non-thermal effects and the thermal effects from cell phone radiation are considered to be less harmful. But, scrotum hyperthermia and increased oxidative stress because of the formation of too much reactive oxygen compounds in the male reproductive system can be key mechanisms through which electromagnetic radiation affects male fertility. However, the negative effects associated with the time of use of the mobile phone are listed above all. Therefore, the goal of this graduate thesis is to describe some of the effects of radiofrequency electromagnetic radiation on the male reproductive system.