Terms mergers and acquisitions have long been present in a business world that only has steady and rapid growth. The most common mode of business growth today, with regard to competition and dynamic of the global market and globalization are mergers and acquisitions. Through these strategies, companies that have chosen this growth strategy use resources, potentials and benefits of the other company to successfully achieve their common goal. The main goal of this final paper is to define terms mergers and acquisitions, the reasons for which companies decide on these strategies and the stages through which companies are going through, to have the opportunity to operate with success. The purpose is to explore and analyze different examples of mergers and acquisitions in the automotive, telecommunication. pharmaceutical and oil industries and present a comparative table with overview of the success of strategy implementation and further business operation with the influence of different factors. Reason of comparative analysis is to define the problems that arise during and after implementing mergers and acquisitions and to define different factors that have a significant impact on the success of the strategy.