Metabolic syndrome is a set of disorders that includes hyperlipidemia, inadequate insulin resistance, hypertension, and abdominal obesity. Patients suffering from this syndrome are at increased risk for heart and blood vessel disease, stroke, and type II diabetes. Stress is considered one of the causes because it disrupts hormonal balance and increases the tendency to accumulate fat in the abdomen and dyslipidemias. Obesity is a characteristic of this syndrome, typically central obesity, where fat accumulates mainly around the waist. In the treatment of the metabolic syndrome, it is crucial to recognize the symptoms early and take action that will reduce the presence of risk factors. Health tourism has been poorly researched, so there is still no established and broadly accepted definition of tourism in foreign and Croatian literature. That is why health tourism often includes hospitals (thalassotherapies, spas, etc.), which bring patients from distant areas to hospital care. The history of man's development shows that the better he lived, the more he cared for his health and wanted to feel better. Mineral, seawater and plain water have played a very important role in the recovery of human health, especially thermal water, which has been known since ancient times. This paper proposes a combination of tourism and medicine as an example of the treatment of metabolic syndrome.