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master's thesis
Genomska procjena inbridinga na temelju markera spolnih kromosoma
Zagreb: University of Zagreb, Faculty of Agriculture, 2016. urn:nbn:hr:204:231168
Šantek, Martina
University of Zagreb
Faculty of Agriculture
Animal Science

Institutional repository: Repository Faculty of Agriculture University of Zagreb

Cite this document

Šantek, M. (2016). Genomska procjena inbridinga na temelju markera spolnih kromosoma (Master's thesis). Zagreb: University of Zagreb, Faculty of Agriculture. Retrieved from https://urn.nsk.hr/urn:nbn:hr:204:231168

Šantek, Martina. "Genomska procjena inbridinga na temelju markera spolnih kromosoma." Master's thesis, University of Zagreb, Faculty of Agriculture, 2016. https://urn.nsk.hr/urn:nbn:hr:204:231168

Šantek, Martina. "Genomska procjena inbridinga na temelju markera spolnih kromosoma." Master's thesis, University of Zagreb, Faculty of Agriculture, 2016. https://urn.nsk.hr/urn:nbn:hr:204:231168

Šantek, M. (2016). 'Genomska procjena inbridinga na temelju markera spolnih kromosoma', Master's thesis, University of Zagreb, Faculty of Agriculture, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:204:231168

Šantek M. Genomska procjena inbridinga na temelju markera spolnih kromosoma [Master's thesis]. Zagreb: University of Zagreb, Faculty of Agriculture; 2016 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:204:231168

M. Šantek, "Genomska procjena inbridinga na temelju markera spolnih kromosoma", Master's thesis, University of Zagreb, Faculty of Agriculture, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:204:231168

Metadata
TitleGenomska procjena inbridinga na temelju markera spolnih kromosoma
AuthorMartina Šantek
MentorIno Čurik (mentor)
Committee memberIno Čurik (predsjednik povjerenstva)
Committee memberMiroslav Kapš (član povjerenstva)
Committee memberVlatka Čubrić Čurik (član povjerenstva)
Committee memberMaja Ferenčaković (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Agriculture
(Animal Science)
Zagreb
Defense date and country2016-09-27, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Agronomy
Genetics and Breeding of Plants, Animals and Microorganisms
Abstract
Inbriding, odnosno parenje jedinki u srodstvu se mjeri koeficijentom inbridinga, F. Do vrijednosti koeficijenta inbridinga se može doći na više načina, jedan od kojih je procjena inbridinga pomoću određivanja homozigotnih odsječaka (ROH). Genomski koeficijent inbridinga se obično odnosi na autosome, dok se inbriding na X kromosomu zanemaruje. U ovom radu su određeni ROH-ovi >4 Mb, >8 Mb i >16 Mb kod jedinki populacije Soay ovaca genotipiziranih Ovine 50K SNP čipom te su određene vrijednosti koeficijenata inbridinga za autosome i X kromosom. Za autosome su određene vrijednosti ukupno za sve kromosome te posebno za svaki kromosom. Inbriding na X kromosomu je ~4 do 15 puta veći nego na autosomima, a vrijednosti za autosomalni i X inbriding uvelike razlikuju kod pojedinih jedinki te je korelacija između vrijednosti niska. X inbriding može biti važan kod vrsta kojima veći dio genoma čini X kromosom te kod kojih su neka važna svojstva djelomično određena genima na X kromosomu te stoga ne smije biti zanemarivan.
Abstract (english)
Inbreeding or mating of related individuals is measured by the coefficient of inbreeding, F. There are more ways to calculate the coefficient of inbreeding, one of which is estimating inbreeding with use of homozygous runs (ROHs). Genomic inbreeding coefficient is usually based on the autosomal chromosomes, while the inbreeding on the X chromosome is neglected. In this thesis, ROHs>4 Mb, >8 Mb and >16 Mb are detected in individuals from Soay sheep population genotyped with Ovine 50K SNP chip and coefficients of inbreeding are determined for autosomal chromosomes and X chromosome. In addition, coefficients of inbreeding are determined for every autosomal chromosome, separately. Detected inbreeding on X chromosome is ~4 to 15 times higher than on the autosomal chromosomes, and values for autosomal and X-chromosomal inbreeding differ a lot in individuals and the correlation between two values is low. X inbreeding can be important in species that have most of their genome located on the X chromosome and those who have some important traits partially determined by genes on X chromosome and therefore must not be neglected.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:204:231168
Study programmeTitle: Animal Genetics and Breeding
Study programme type: university
Study level: graduate
Academic / professional title: magistar/ magistra inženjer/inženjerka genetike i oplemenjivanja životinja (magistar/ magistra inženjer/inženjerka genetike i oplemenjivanja životinja)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2016-11-30 07:21:57