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undergraduate thesis
Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline
završni rad
Split: University of Split, Faculty of Chemistry and Technology, 2017. urn:nbn:hr:167:022533
Jolić, Nina
University of Split
Faculty of Chemistry and Technology
Division of Engineering and Chemistry

Institutional repository: Repository of the Faculty of chemistry and technology

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Jolić, N. (2017). Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad (Undergraduate thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:022533

Jolić, Nina. "Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:167:022533

Jolić, Nina. "Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:167:022533

Jolić, N. (2017). 'Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad', Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:167:022533

Jolić N. Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad [Undergraduate thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2017 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:167:022533

N. Jolić, "Antioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad", Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, Split, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:167:022533

Metadata
TitleAntioksidacijska aktivnost fenola: interakcija derivata hidroksibenzojeve kiseline : završni rad
Title (english)Antioxidant activity of phenolics: interaction between hydroxybenzoic acid derivatives : bachelor thesis
AuthorNina Jolić
MentorIvana Generalić Mekinić (mentor)
Committee memberFranko Burčul (predsjednik povjerenstva)
Committee memberDanijela Skroza (član povjerenstva)
Committee memberIvana Generalić Mekinić (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Engineering and Chemistry)
Split
Defense date and country2017-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Abstract
Posljednjih godina sve više raste interes znanstvenika za fenolne spojeve zbog njihove dokazane biološke aktivnosti koja ih čini zanimljivima farmaceutskoj, kozmetičkoj i prehrambenoj industriji. U ovom završnom radu zadatak je bio odrediti antioksidacijsku aktivnost pet hidroksibenzojevih kiselina, i to galne, vanilinske, protokatehinske, siriginske i gentisinske kiseline, FRAP metodom. Osim čistih spojeva testirane su ekvimolarne smjese navedenih fenolnih kiselina pri različitim koncentracijama (50, 100, 1000 μM) u kojima su bile kombinacije dvije, tri, četiri te svih pet spojeva. Eksperimentalno dobivene redukcijske aktivnosti smjesa su uspoređene sa izračunatim teoretskim vrijednostima te je na taj način dokazano postojanje aditivnog, sinergijskog ili antagonističkog učinka. Zaključeno je kako interakcija i učinak fenolnih spojeva u smjesama uvelike ovisi o koncentracijama u kojim su navedeni spojevi prisutni. Najveću sinergiju je pokazala smjesa protokatehinske, siriginske i gentisinske kiseline pri koncentraciji od 100 µM dok je pri istoj koncentraciji najveći antagonizam pokazala smjesa vanilinske i protokatehinske kiseline.
Abstract (english)
In last few years, there has been a growing interest in phenolic compounds due to their biological activities which make them interesting to the pharmaceutical, cosmetic and food industries. The aim of this work was to determine antioxidant activity of five hydroxybenzoic acids; gallic, vanillic, protocatechuic, syringic and gentisic acid using the FRAP assay. Besides pure phenolic compounds, the equimolar mixtures of the investigated acids were also tested at different concentrations (50, 100, 1000 μM) as well as combinations of two, three, four and all five acids. The experimental results were compared with the theoretical values, thus proving the existence of an additive, synergistic or antagonistic effect. It can be concluded that interaction of investigated phenolic compounds depends on concentrations in which the compounds are present. The highest synergy effect was observed for the mixture of protocatechuic, syringic and gentisic acid at concentration of 100 μM while the highest antagonism was detected for the mixture of vanillic and protocatechuic acid at same concentration.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:022533
ProjectNumber: IP-2014-09-6897
Title: Istraživanje bioaktivnih spojeva iz dalmatinskogbilja: njihov antioksidacijski karakter i utjecaj na enzimsku inhibiciju i zdravlje
Acronym: BioActCom
Leader: Mladen Miloš
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Chemical Technology; specializations in: Chemical Technology and Materials, Food Technology
Course: Chemical Technology and Materials
Study programme type: professional
Study level: undergraduate
Academic / professional title: stručni/a pristupnik/pristupnica kemijskog inženjerstva (stručni/a pristupnik/pristupnica kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Public noteKljučne riječi doradio knjižničar/ Key words are revised by the librarian
Created on2018-04-27 09:02:17